Research library - LIPID MAPS Publications: 2009

Key Lipidomics Publications

Special issues, with significant contributions from members of the LIPID MAPS Consortium

Lipid Biochemistry, Metabolism, and Signaling Editorial
Edited by H. Alex Brown and Lawrence J. Marnett. Chemical Reviews, 111, 5817-6512 (2011)
Lipidomics and Imaging Mass Spectrometry
Edited by Alfred H. Merrill and Robert C. Murphy. BBA - Molecular and Cellular Biology of Lipids, 1811, 635-1000 (2011)
Lipidomics and Bioactive Lipids: Mass-Spectrometry-Based Lipid Analysis
Edited by H. Alex Brown. Methods in Enzymology, 432, 1-387 (2007)
- Download all LIPID MAPS Chapters (PDF).

Peer-reviewed journal articles

A community-driven global reconstruction of human metabolism.
Nat Biotechnol. 2013 May;31(5):419-25. doi: 10.1038/nbt.2488. Epub 2013 Mar 3.
Macrophages, Inflammation, and Insulin Resistance
Jerrold M. Olefsky, Christopher K. Glass Annual Review of Physiology, 72 219-246 (2010)

more key publications

LIPID MAPS Publications

Year published: 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017

2009

Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2

Bae YS, Lee JH, Choi SH, Kim S, Almazan F, Witztum JL, Miller YI

Circulation Research 104, 210-18 (2009)

PMID:19096031 [10.1161/CIRCRESAHA.108.181040]
Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC

Barb AW, Leavy TM, Robins LI, Guan Z, Six DA, Zhou P, Bertozzi CR, Raetz CR

Biochemistry 48, 3068-77 (2009)

PMID:19256534 [10.1021/bi900167q]
2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides

Barbayianni E, Stephens D, Grkovich A, Magrioti V, Hsu YH, Dolatzas P, Kalogiannidis D, Dennis EA, Kokotos G

Bioorganic and Medical Chemistry 17, 4833-43 (2009)

PMID:19443224 [10.1016/j.bmc.2009.03.069]
Crystal structure and acyl chain selectivity of Escherichia coli LpxD, the N-acyltransferase of lipid A biosynthesis

Bartling CM, Raetz CR

Biochemistry 48, 8672-83 (2009)

PMID:19655786 [10.1021/bi901025v]
Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation

Basselin M, Kim HW, Chen M, Ma K, Rapoport SI, Murphy RC, Farias SE

Journal of Lipid Research in press

PMID:20040630 [10.1194/jlr.M002469]
25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production

Bauman DR, Bitmansour AD, McDonald JG, Thompson BM, Liang G, Russell DW
Proceedings of the National Academy of Science USA 106, 16764-9 (2009)

PMID:19805370 [10.1073/pnas.0909142106]
Stable Isotope Labeled 4-(Dimethylamino)benzoic Acid Derivatives of Glycerophosphoethanolamine Lipids

Berry KAZ, Turner WW, VanNieuwenhze MS, Murphy RC

Analytical Chemistry 81, 6633-6640 (2009)

[10.1021/Ac900583a]
Lipidomic analysis of dynamic eicosanoid responses during the induction and resolution of lyme arthritis.

Blaho V, Buczynski M, Brown C and Dennis E.

The Journal of Biological Chemistry 284, 21599-21612 (2009)

PMID:19487688 [10.1074/jbc.M109.003822]
Cyclooxygenase-1 orchestrates germinal center formation and antibody class-switch via regulation of IL-17

Blaho VA, Buczynski MW, Brown CR, Dennis EA

Journal of Immunology 183, 5644-53 (2009)

PMID:19843949 [10.4049/jimmunol.0901499]
An integrated omics analysis of eicosanoid biology.

Buczynski M, Dumlao D and Dennis E.

Journal of Lipid Research 50, 1015-38 (2009)

PMID:19244215 [10.1194/jlr.R900004-JLR200]
Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation

Burnum KE, Cornett DS, Puolitaival SM, Milne SB, Myers DS, Tranguch S, Brown HA, Dey SK, Caprioli RM

Journal of Lipid Research 50, 2290-2298 (2009)

PMID:19429885 [10.1194/jlr.M900100-JLR200]
An editor for pathway drawing and data visualization in the Biopathways Workbench

Byrnes RW, Cotter D, Maer A, Li J, Nadeau D, Subramaniam S

BMC Systems Biology 3, 99 (2009)

PMID:19799790 [10.1186/1752-0509-3-99]
Mutational analysis of Burkholderia thailandensis quorum sensing and self-aggregation

Chandler JR, Duerkop BA, Hinz A, West TE, Herman JP, Churchill ME, Skerrett SJ, Greenberg EP

Journal of Bacteriology 191, 5901-9 (2009)

PMID:19648250 [10.1128/JB.00591-09]
Lipoprotein accumulation in macrophages via TLR4-dependent fluid phase uptake

Choi SH, Harkewicz R, Lee JH, Boullier A, Almazan F, Li AC, Witztum JL, Bae YS, Miller YI

Circulation Research 104, 1355-63 (2009)

PMID:19461045 [10.1161/CIRCRESAHA.108.192880]
Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway

Coward J, Ambrosini G, Musi E, Truman JP, Haimovitz-Friedman A, Allegood JC, Wang E, Merrill AH, Jr., Schwartz GK

Autophagy 5, 184-93 (2009)

PMID:19098447 [10.4161/auto.5.2.7361]
Acid sphingomyelinase deficiency prevents diet-induced hepatic triacylglycerol accumulation and hyperglycemia in mice.

Deevska G, Rozenova K, Giltiay N, Chambers M, White J, Boyanovsky B, Wei J, Daugherty A, Smart E, Reid M, Merrill JA and Nikolova-Karakashian M.

The Journal of Biological Chemistry 284, 8359-8368 (2009)

PMID:19074137 [10.1074/jbc.M807800200]
Lipidomics joins the omics evolution.

Dennis E.

Proceedings of the National Academy of Sciences USA 106, 2089-2090 (2009)

PMID:19211786 [10.1073/pnas.0812636106]
Update of the LIPID MAPS comprehensive classification system for lipids.

Fahy E, Subramaniam S, Murphy R, Nishijima M, Raetz C, Shimizu T, Spener F, van Meer G, Wakelam M and Dennis E.

Journal of Lipid Research 50, S9-S14 (2009)

PMID:19098281 [10.1194/jlr.R800095-JLR200]
Identification of phosphatidylserylglutamtate: A novel minor lipid in Escherichia coli

Garrett TA, Raetz CR, Richardson T, Kordestani R, Son JD, Rose RL

Journal of Lipid Research 50, 1589-99 (2009)

PMID:19096047 [10.1194/jlr.M800549-JLR200]
Internal energy of molecules ejected due to energetic C(60) bombardment.

Garrison B, Postawa Z, Ryan K, Vickerman J, Webb R and Winograd N.

Analytical Chemistry 81, 2260-2267 (2009)

PMID:19228010 [10.1021/ac802399m]
Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, Glass CK

Genes & Development 23, 681-93 (2009)

PMID:19299558 [10.1101/gad.1773109]
TLR-4 mediated group GIVA phospholipase A2 activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent

Grkovich A, Armando A, Quehenberger O, Dennis EA

Biochimica and Biophysica Acta 1791, 975-982 (2009)

PMID:19230851 [10.1016/j.bbalip.2009.02.002]
Discovering novel brain lipids by liquid chromatography/tandem mass spectrometry

Guan Z

Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences Epub ahead of print

PMID:19303823 [10.1016/j.jchromb.2009.03.002]
An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis

Gupta S, Maurya MR, Stephens DL, Dennis EA, Subramaniam S

Biophysical Journal 96, 4542-51 (2009)

PMID:19486676 [10.1016/j.bpj.2009.03.011]
Subcellular origin of sphingosine-1-phosphate is essental for its toxic effect in lyase deficient neurons.

Hagen N, van Veldhoven P, Proia R, Park H, Merrill JA and van Echten-Deckert G.

The Journal of Biological Chemistry 284, 11346-11353 (2009)

PMID:19251691 [10.1074/jbc.M807336200]
Sphingolipidomics: methods for the comprehensive analysis of sphingolipids

Haynes CA, Allegood JC, Park H, Sullards MC

Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences 877, 2696-708 (2009)

PMID:19147416 [10.1016/j.jchromb.2008.12.057]
Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates

Holinstat M, Preininger AM, Milne SB, Hudson WJ, Brown HA, Hamm HE

Molecular Pharmacology 76, 301-13 (2009)

PMID:19483102 [10.1124/mol.109.056622]
Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint

Huang W, Ghisletti S, Perissi V, Rosenfeld MG, Glass CK

Molecular Cell 35, 48-57 (2009)

PMID:19595715 [10.1016/j.molcel.2009.05.023]
Identification of atypical ether-linked glycerophospholipid species in macrophages by mass spectrometry

Ivanova PT, Milne SB, Brown HA

Journal of Lipid Research Epub ahead of print

PMID:19965583 [10.1194/jlr.D003715]
Lipidomics: a mass spectrometry based systems level analysis of cellular lipids

Ivanova PT, Milne SB, Myers DS, Brown HA

Current Opinions in Chemical Biology 13, 526-31 (2009)

PMID:19744877 [10.1016/j.cbpa.2009.08.011]
Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol

Lung M, Shulga YV, Ivanova PT, Myers DS, Milne SB, Brown HA, Topham MK, Epand RM

Journal of Biological Chemistry 284, 31062-73 (2009)

PMID:19744926 [10.1074/jbc.M109.050617]
Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity.

Marlo J, Niswender C, Days E, Bridges T, Xiang Y, Rodriguez A, Shirey J, Brady A, Nalywajko T, Luo Q, Austin C, Williams M, Kim K, Williams R, Orton D, Brown H, Lindsley C, Weaver C and Conn P.

Molecular Pharmacology 75, 577-588 (2009)

PMID:19047481 [10.1124/mol.108.052886]
A mixed-integer nonlinear optimization approach to coarse-graining biochemical networks

Maurya MR, Bornheimer SJ, Venkatasubramanian V, Subramaniam S

IET Systems Biology 3, 24-39 (2009)

PMID:19154082 [10.1049/iet-syb:20080098]
Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease

Merrill AH, Jr., Stokes TH, Momin A, Park H, Portz BJ, Kelly S, Wang E, Sullards MC, Wang MD

Journal of Lipid Research 50, Suppl S97-102 (2009)

PMID:19029065 [10.1194/jlr.R800073-JLR200]
Purification and characterization of the lipid A disaccharide synthase (LpxB) from Escherichia coli, a peripheral membrane protein

Metzger LEt, Raetz CR

Biochemistry 48, 11559-71 (2009)

PMID:19883124 [10.1021/bi901750f]
Phosphatidic acid and N-acylphosphatidylethanolamine form membrane domains in Escherichia coli mutant lacking cardiolipin and phosphatidylglycerol

Mileykovskaya E, Ryan AC, Mo X, Lin CC, Khalaf KI, Dowhan W, Garrett TA

Journal of Biological Chemistry 284, 2990-3000 (2009)

PMID:19049984 [10.1074/jbc.M805189200]
Imaging of lipid species by MALDI mass spectrometry.

Murphy R, Hankin J and Barkley R.

Journal of Lipid Research 50, S317-S322 (2009)

PMID:19050313 [10.1194/jlr.R800051-JLR200]
Mycobacterium tuberculosis Rv3802c encodes a phospholipase/thioesterase and is inhibited by the antimycobacterial agent tetrahydrolipstatin

Parker SK, Barkley RM, Rino JG, Vasil ML

PLoS ONE 4, e4281 (2009)

PMID:19169353 [10.1371/journal.pone.0004281]
Molecular Dynamics Simulations of Sputtering of Langmuir-Blodgett Multilayers by Kiloelectronvolt C-60 Projectiles

Paruch R, Rzeznik L, Czerwinski B, Garrison BJ, Winograd N, Postawa Z

Journal of Physical Chemistry C 113, 5641-5648 (2009)

[10.1021/Jp809769q]
Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice

Poeckel D, Zemski Berry KA, Murphy RC, Funk CD

Journal of Biological Chemistry 284, 21077-89 (2009)

PMID:19509298 [10.1074/jbc.M109.000901]
Discovery of new biosynthetic pathways: the lipid A story

Raetz CR, Guan Z, Ingram BO, Six DA, Song F, Wang X, Zhao J

Journal of Lipid Research 50, Suppl S103-8 (2009)

PMID:18974037 [10.1194/jlr.R800060-JLR200]
Lipidomics profiling in mouse brain reveals differences between ages and genders with smaller changes associated with α-synuclein genotype

Rappley I, Myers DS, Milne SB, Ivanova PT, LaVoie MJ, Brown HA, Selkoe DJ

Journal of Neurochemistry 111, 15-25 (2009)

PMID:19627450 [10.1111/j.1471-4159.2009.06290.x]
Replacement of lipopolysaccharide with free lipid A molecules in Escherichia coli mutants lacking all core sugars

Reynolds CM, Raetz CR

Biochemistry 48, 9627-40 (2009)

PMID:19754149 [10.1021/bi901391g]
Cardiolipin and the osmotic stress responses of bacteria

Romantsov T, Guan Z, Wood JM

Biochimca and Biophysica Acta 1788, 2092-100 (2009)

[10.1016/j.bbamem.2009.06.010]
Cholesterol 24-Hydroxylase: An Enzyme of Cholesterol Turnover in the Brain

Russell DW, Halford RW, Ramirez DMO, Shah R, Kotti T

Annual Reviews in Biochemistry 78, 1017-40 (2009)

PMID:19489738 [10.1146/annurev.biochem.78.072407.103859]
A Eukaryote-like Cardiolipin Synthase is Present in Streptomyces Coelicolor and in most Actinobacteria

Sandoval-Calderon M, Geiger O, Guan Z, Barona-Gomez F, Sohlenkamp C

Journal of Biological Chemistry 284, 17383-17390 (2009)

PMID:19439403 [10.1074/jbc.M109.006072]
pH dependence of sphingosine aggregation

Sasaki H, Arai H, Cocco MJ, White SH

Biophysical Journal 96, 2727-33 (2009)

PMID:19348755 [10.1016/j.bpj.2008.12.3926]
A novel fluorescent probe that senses the physical state of lipid bilayers

Sasaki H, White S

Biophysical Journal 96, 4631-41 (2009)

PMID:19486685 [10.1016/j.bpj.2009.03.003]
Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization

Sears DD, Hsiao G, Hsiao A, Yu JG, Courtney CH, Ofrecio JM, Chapman J, Subramaniam S

Proceedings of the National Academy of Sciences USA 106, 18745-50 (2009)

PMID:19841271 [10.1073/pnas.0903032106]
Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers

Shaner RL, Allegood JC, Park H, Wang E, Kelly S, Haynes CA, Sullards MC, Merrill AH, Jr.

Journal of Lipid Research 50, 1692-707 (2009)

PMID:19036716 [10.1194/jlr.D800051-JLR200]
Regulation of macrophage function in inflammation and atherosclerosis Shibata N, Glass CK

Journal of Lipid Research
50, Suppl S277-81 (2009)

PMID:18987388 [10.1194/jlr.R800063-JLR200]
Biosynthesis of undecaprenyl phosphate-galactosamine and undecaprenyl phosphate-glucose in francisella novicida .

Song F, Guan Z and Raetz CRH.

Biochemistry 48, 1173-82 (2009)

PMID:19166326 [10.1021/bi802212t]
CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions

Stiles AR, McDonald JG, Bauman DR, Russell DW

Journal of Biological Chemistry 284, 28485-9

PMID:19687010 [10.1074/jbc.R109.042168]
Identification of undecaprenyl phosphate-beta-d-galactosamine in francisella novicida and its function in lipid A modification .

Wang X, Ribeiro A, Guan Z and Raetz C.

Biochemistry (2009) 48, 1162-72 (2009)

PMID:19166327 [10.1021/bi802211k]
Altered sphingolipid metabolism induced by tumor hypoxia - New vistas in glycolipid tumor markers

Yin J, Miyazaki K, Shaner RL, Merrill AH, Jr., Kannagi R

FEBS Letters Epub ahead of print (2009)

PMID:19913543 [10.1016/j.febslet.2009.11.019]
Phospholipase D1 is required for angiogenesis of intersegmental blood vessels in zebrafish

Zeng XX, Zheng X, Xiang Y, Cho HP, Jessen JR, Zhong TP, Solnica-Krezel L, Brown HA

Developmental Biology 328, 363-76 (2009)

PMID:19389349 [10.1016/j.ydbio.2009.01.035]
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals.

Zitomer N, Mitchell T, Voss K, Bondy G, Pruett S, Garnier-Amblard E, Liebeskind L, Park H, Wang E, Sullards M, Merrill JA and Riley R.

The Journal of Biological Chemistry 284, 4786-4795 (2009)

PMID:19095642 [10.1074/jbc.M808798200]

Research library - LIPID MAPS Publications: 2009

Key Lipidomics Publications

LIPID MAPS Publications

2009

Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2

Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC

2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides

Crystal structure and acyl chain selectivity of Escherichia coli LpxD, the N-acyltransferase of lipid A biosynthesis

Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation

25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production

Stable Isotope Labeled 4-(Dimethylamino)benzoic Acid Derivatives of Glycerophosphoethanolamine Lipids

Lipidomic analysis of dynamic eicosanoid responses during the induction and resolution of lyme arthritis.

Cyclooxygenase-1 orchestrates germinal center formation and antibody class-switch via regulation of IL-17

An integrated omics analysis of eicosanoid biology.

Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation

An editor for pathway drawing and data visualization in the Biopathways Workbench

Mutational analysis of Burkholderia thailandensis quorum sensing and self-aggregation

Lipoprotein accumulation in macrophages via TLR4-dependent fluid phase uptake

Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway

Acid sphingomyelinase deficiency prevents diet-induced hepatic triacylglycerol accumulation and hyperglycemia in mice.

Lipidomics joins the omics evolution.

Update of the LIPID MAPS comprehensive classification system for lipids.

Identification of phosphatidylserylglutamtate: A novel minor lipid in Escherichia coli

Internal energy of molecules ejected due to energetic C(60) bombardment.

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

TLR-4 mediated group GIVA phospholipase A2 activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent

Discovering novel brain lipids by liquid chromatography/tandem mass spectrometry

An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis

Subcellular origin of sphingosine-1-phosphate is essental for its toxic effect in lyase deficient neurons.

Sphingolipidomics: methods for the comprehensive analysis of sphingolipids

Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates

Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint

Identification of atypical ether-linked glycerophospholipid species in macrophages by mass spectrometry

Lipidomics: a mass spectrometry based systems level analysis of cellular lipids

Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol

Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity.

A mixed-integer nonlinear optimization approach to coarse-graining biochemical networks

Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease

Purification and characterization of the lipid A disaccharide synthase (LpxB) from Escherichia coli, a peripheral membrane protein

Phosphatidic acid and N-acylphosphatidylethanolamine form membrane domains in Escherichia coli mutant lacking cardiolipin and phosphatidylglycerol

Imaging of lipid species by MALDI mass spectrometry.

Mycobacterium tuberculosis Rv3802c encodes a phospholipase/thioesterase and is inhibited by the antimycobacterial agent tetrahydrolipstatin

Molecular Dynamics Simulations of Sputtering of Langmuir-Blodgett Multilayers by Kiloelectronvolt C-60 Projectiles

Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice

Discovery of new biosynthetic pathways: the lipid A story

Lipidomics profiling in mouse brain reveals differences between ages and genders with smaller changes associated with α-synuclein genotype

Replacement of lipopolysaccharide with free lipid A molecules in Escherichia coli mutants lacking all core sugars

Cardiolipin and the osmotic stress responses of bacteria

Cholesterol 24-Hydroxylase: An Enzyme of Cholesterol Turnover in the Brain

A Eukaryote-like Cardiolipin Synthase is Present in Streptomyces Coelicolor and in most Actinobacteria

pH dependence of sphingosine aggregation

A novel fluorescent probe that senses the physical state of lipid bilayers

Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization

Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers

Regulation of macrophage function in inflammation and atherosclerosis Shibata N, Glass CK

Biosynthesis of undecaprenyl phosphate-galactosamine and undecaprenyl phosphate-glucose in francisella novicida .

CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions

Identification of undecaprenyl phosphate-beta-d-galactosamine in francisella novicida and its function in lipid A modification .

Altered sphingolipid metabolism induced by tumor hypoxia - New vistas in glycolipid tumor markers

Phospholipase D1 is required for angiogenesis of intersegmental blood vessels in zebrafish

Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals.