Michal obtained his Ph.D. at the Department of Analytical Chemistry, University of Pardubice. Now he is a full professor of analytical chemistry at the same university. The research focus is in mass spectrometry and its coupling with liquid chromatography and supercritical fluid chromatography, applied mainly in the lipidomic analysis and cancer biomarker research.

He obtained several scientific awards, such as the Power List of 100 most influential people in the analytical sciences (2020, 2015 and 2013, The Analytical Scientist). He is a co-author of 148 papers in peer-reviewed international journals, h-index 43, contributing editor of Trends in Analytical Chemistry, member of editorial advisory boards of Analytical and Bioanalytical Chemistry, Lipids.

He was an co-editor of books Handbook of Advanced Chromatography/Mass Spectrometry Techniques (Academic Press and AOCS Press, 2017) and Extreme Chromatography: Faster, Hotter, Smaller (American Oil Chemical Society, 2011), editor of topical collections in Analytical Chemistry, Analytical and Bioanalytical Chemistry, and Journal of Chromatography A, former head of Czech Mass Spectrometry Section in I.M.M. Spectroscopic Society and national representative in International Mass Spectrometry Foundation (2005-13), the chairman of over ten international and national conferences, e.g., HPLC 2017 Prague, 3rd European Lipidomic Meeting in 2013, etc.

He is one of founding members of Lipidomics Standards Initiative and vice-president for conferences in the International Lipidomics Society.