Pathways

Pathway maps drawn using VANTED software

Pathway maps are *.png image files
Tabular data for lipids includes links to time course graphs, data for technical and biological replicates, and the LMSD record with lipid structure and annotations. Tabular data for genes includes links to time course graphs and annotations.

RAW 264.7 cells: Kdo₂-Lipid A time course experiments

• Eicosanoids
  • Pathway map Eicosanoids [media]
  • Tabular data Eicosanoids [media]
• Fatty Acids
  • Pathway maps
    • Omega-3 and omega-6 fatty acids [cells]
    • Omega-9 and other fatty acids [cells]
    • Omega-3 and omega-6 fatty acids [media]
    • Omega-9 and other fatty acids [media]
  • Tabular data Fatty acids [cells]
• Glycerolipids and Glycerophospholipids
  • Pathway maps (acyl chains):
    32:0 32:1 34:0 34:1 36:0 36:1 38:0 38:1 38:4
  • Tabular data
• Sphingolipids
  • Pathway maps (N-acyl chains): C16 C18 C20 C22 C24 C24:1 C26 C26:1
    All chain lengths
  • Tabular data
• Sterol Lipids
  • Pathway display
  • Expanded pathway display (Includes both Bloch and Kandustch-Russell pathways)
  • Tabular data
• Signaling pathways
  • Apoptosis pathway
  • Cell cycle pathway
  • PI3K/Akt/mTOR pathway
  • PPAR (Peroxisome proliferator-activated receptor) pathway
  • TLR4 (Toll-like receptor 4) pathway

RAW 264.7 cells: Compactin/Kdo₂-Lipid A time course experiments

• Eicosanoids
  • Pathway display Eicosanoids [media]
  • Tabular data Eicosanoids [media]
• Fatty Acids
  • Pathway displays
    • Omega-3 and omega-6 fatty acids [cells]
    • Omega-9 and other fatty acids [cells]
  • Tabular data Fatty acids [cells]
• Glycerolipids/Glycerophospholipids
  • Pathway display(acyl chains): 32:0 32:1 34:0 34:1 36:0 36:1 38:0 38:1 38:4
  • Tabular data GL
  • Tabular data GP
• Sphingolipids
  • Pathway display(N-acyl chain): C16 C18 C20 C22 C24 C24:1 C26 C26:1
    All chain lengths
  • Tabular data
• Sterol lipids
  • Pathway display
  • Expanded pathway display (Incldues both Bloch and Kandustch-Russell pathways)
  • Tabular data
• Signaling pathways
  • Apoptosis pathway
  • Cell cycle pathway
  • PI3K/Akt/mTOR pathway
  • PPAR (Peroxisome proliferator-activated receptor) pathway
  • TLR4 (Toll-like receptor 4) pathway

RAW 264.7 cells: POVPC/ATP time course experiments

• Eicosanoids
  • Pathway display Eicosanoids [media]
  • Tabular data Eicosanoids [media]
• Fatty Acids
  • Pathway displays
    • Omega-3 and omega-6 fatty acids [cells]
    • Omega-9 and other fatty acids [cells]
  • Tabular data Fatty acids [cells]
• Glycerolipids/Glycerophospholipids
  • Pathway display(acyl chains): 32:0 32:1 34:1 36:1 38:4
  • Tabular data: MAG 1,2-DAG TAG GP CL
• Sphingolipids
  • Pathway display(N-acyl chain): C16 C18 C20 C22 C24 C24:1 C26 C26:1
    All chain lengths
  • Tabular data
• Sterol lipids
  • Pathway display
  • Expanded pathway display (Incldues both Bloch and Kandustch-Russell pathways)
  • Tabular data
• Signaling pathways
  • Apoptosis pathway
  • Cell cycle pathway
  • PI3K/Akt/mTOR pathway
  • PPAR (Peroxisome proliferator-activated receptor) pathway
  • TLR4 (Toll-like receptor 4) pathway

Thioglycolate-elicited peritoneal macrophages: Compactin/Kdo₂-Lipid A time course experiments

• Eicosanoids
  • Pathway display Eicosanoids [media]
  • Tabular data Eicosanoids [media]
• Fatty Acids
  • Pathway displays
    • Omega-3 and omega-6 fatty acids [cells]
    • Omega-9 and other fatty acids [cells]
  • Tabular data Fatty acids [cells]
• Glycerolipids/Glycerophospholipids
  • Pathway display(acyl chains): 32:0 32:1 34:0 34:1 36:0 36:1 38:0 38:1 38:4
  • Tabular data
• Sphingolipids
  • Pathway display(N-acyl chain): C16 C18 C20 C22 C24 C24:1 C26 C26:1
    All chain lengths
  • Tabular data
• Sterol lipids
  • Pathway display
  • Expanded pathway display (Incldues both Bloch and Kandustch-Russell pathways)
  • Tabular data
• Signaling pathways
  • Apoptosis pathway
  • Cell cycle pathway
  • PI3K/Akt/mTOR pathway
  • PPAR (Peroxisome proliferator-activated receptor) pathway
  • TLR4 (Toll-like receptor 4) pathway

Bone marrow-derived macrophages: ATP/Kdo₂-Lipid A time course experiments (pmol/ug DNA) [Averaged DNA values]

• Eicosanoids
  • Pathway display
    • Detailed display: Eicosanoids [media]: COX pathway LOX pathway CYP pathway
    • Simplified display: Eicosanoids [media]
  • Tabular data Eicosanoids [media]
• Fatty Acids
  • Pathway display
    • Omega-3 and omega-6 fatty acids [cells]
    • Omega-9 and other fatty acids [cells]
  • Tabular data Fatty acids [cells]
• Glycerolipids/Glycerophospholipids
  • Pathway display (acyl chains): 32:0 32:1 34:0 34:1 36:0 36:1 38:0 38:1 38:4
  • Tabular data
• Sphingolipids
  • Pathway display (N-acyl chain): C16 C18 C20 C22 C24 C24:1 C26 C26:1
    All chain lengths
  • Tabular data
• Sterol lipids
  • Pathway display
  • Expanded pathway display (Incldues both Bloch and Kandustch-Russell pathways)
  • Tabular data
• Signaling pathways
  • Apoptosis pathway
  • Cell cycle pathway
  • PI3K/Akt/mTOR pathway pathway
  • PPAR (Peroxisome proliferator-activated receptor) pathway
  • TLR4 (Toll-like receptor 4) pathway

Bone marrow-derived macrophages: 25-hydroxy-cholesterol time course experiments (pmol/sample)

• Eicosanoids
  • Pathway display Eicosanoids [media]
  • Tabular data Eicosanoids [media]
• Fatty Acids
  • Pathway display
    • Omega-3 and omega-6 fatty acids [cells]
    • Omega-9 and other fatty acids [cells]
  • Fatty acids [cells]
• Glycerolipids/Glycerophospholipids
  • Pathway display (acyl chains): 32:0 32:1 34:0 34:1 36:0 36:1 38:0 38:1 38:4
  • Tabular data
• Sphingolipids
  • Pathway display (N-acyl chain): C16 C18 C20 C22 C24 C24:1 C26 C26:1
    All chain lengths
  • Tabular data
• Sterol lipids
  • Pathway display
  • Expanded pathway display (Incldues both Bloch and Kandustch-Russell pathways)
  • Tabular data
• Signaling pathways
  • Apoptosis pathway
  • Cell cycle pathway
  • PI3K/Akt/mTOR pathway
  • PPAR (Peroxisome proliferator-activated receptor) pathway
  • TLR4 (Toll-like receptor 4) pathway

Pathway maps were created using the VANTED application (http://vanted.ipk-gatersleben.de/). For more information on VANTED, please refer to: Björn H. Junker, Christian Klukas and Falk Schreiber (2006): VANTED: A system for advanced data analysis and visualization in the context of biological networks. BMC Bioinformatics, 7:109 (http://www.biomedcentral.com/1471-2105/7/109)