Microarray analysis of RAW 264.7 cells treated with Kdo₂-lipid A (KLA) and compactin (full time course)

Kdo₂-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Collecting duct acid secretion (mmu04966)

Legend: : View data/graphs for replicates

Gene symbol	Time course plot	Accession	Description	Treatment	30min	1hr	2hr	4hr	8hr	12hr	24hr
Atp4a	KLA  Compactin  Compactin+KLA	NM_018731	ATPase, H+/K+ exchanging, gastric, alpha polypeptide (Atp4a), mRNA [NM_018731]	KLA	0.950	1.050	1.040	1.050	0.980	0.950	0.910
				Compactin	0.940	0.970	0.970	0.990	1.080	0.990	1.010
				KLA/Compactin	1.030	0.980	1.030	1.020	1.040	1.020	0.990
Atp4a	KLA  Compactin  Compactin+KLA	U17282	gastric H(+)-K(+)-ATPase alpha subunit mRNA, complete cds. [U17282]	KLA	1.040	1.000	0.910	1.060	1.010	1.030	1.080
				Compactin	0.980	0.970	0.970	1.020	1.020	1.030	0.970
				KLA/Compactin	0.950	1.000	0.980	1.010	1.010	1.200	1.150
Atp4b	KLA  Compactin  Compactin+KLA	NM_009724	ATPase, H+/K+ exchanging, beta polypeptide (Atp4b), mRNA [NM_009724]	KLA	0.910	1.030	0.990	1.060	1.060	1.030	1.040
				Compactin	1.050	0.980	1.010	0.980	1.080	1.050	1.010
				KLA/Compactin	0.980	1.050	1.040	1.000	1.110	1.060	0.950
Atp4b	KLA  Compactin  Compactin+KLA	NM_009724	ATPase, H+/K+ exchanging, beta polypeptide (Atp4b), mRNA [NM_009724]	KLA	1.040	0.960	0.900	0.980	0.980	1.130	1.010
				Compactin	0.950	1.010	1.060	0.980	1.000	0.990	0.890
				KLA/Compactin	1.000	1.040	1.010	0.980	1.040	0.960	0.970
Atp6v0a1	KLA  Compactin  Compactin+KLA	AK045877	adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230316H04 product:unclassifiable, full insert sequence [AK045877]	KLA	1.340	1.380	1.200	1.390	2.020	1.720	1.180
				Compactin	0.960	1.020	0.860	0.820	1.030	1.030	1.180
				KLA/Compactin	1.220	1.400	1.220	1.520	1.630	1.390	1.540
Atp6v0a1	KLA  Compactin  Compactin+KLA	NM_016920	ATPase, H+ transporting, lysosomal V0 subunit A1 (Atp6v0a1), mRNA [NM_016920]	KLA	0.930	0.990	1.210	1.500	1.600	1.610	1.490
				Compactin	1.040	1.010	1.060	1.130	0.890	0.930	1.040
				KLA/Compactin	0.990	1.060	1.090	1.590	1.610	1.630	1.400
Atp6v0a1	KLA  Compactin  Compactin+KLA	NM_016920	ATPase, H+ transporting, lysosomal V0 subunit A1 (Atp6v0a1), mRNA [NM_016920]	KLA	0.950	1.040	1.180	1.250	1.690	1.820	2.090
				Compactin	0.980	1.030	0.950	1.010	1.010	1.010	1.370
				KLA/Compactin	0.950	1.050	1.160	1.150	1.810	1.850	1.940
Atp6v0a2	KLA  Compactin  Compactin+KLA	AK160318	16 days embryo lung cDNA, RIKEN full-length enriched library, clone:8430408C20 product:unclassifiable, full insert sequence [AK160318]	KLA	0.990	0.880	0.810	0.870	0.850	0.760	0.720
				Compactin	0.890	0.980	0.940	0.830	0.940	1.020	0.970
				KLA/Compactin	1.030	0.870	0.940	0.790	0.720	0.720	0.840
Atp6v0a2	KLA  Compactin  Compactin+KLA	BC112905	ATPase, H+ transporting, lysosomal V0 subunit A2, mRNA (cDNA clone MGC:118073 IMAGE:3670722), complete cds [BC112905]	KLA	1.310	1.190	1.180	1.200	1.190	1.330	0.630
				Compactin	1.110	1.250	1.260	1.070	0.900	0.930	1.190
				KLA/Compactin	1.100	0.970	1.150	1.460	1.270	1.120	0.560
Atp6v0a2	KLA  Compactin  Compactin+KLA	NM_011596	ATPase, H+ transporting, lysosomal V0 subunit A2 (Atp6v0a2), mRNA [NM_011596]	KLA	1.030	1.010	1.110	1.340	1.130	1.730	1.140
				Compactin	1.080	1.080	1.120	1.070	0.960	0.990	1.090
				KLA/Compactin	1.120	1.000	1.190	1.390	1.430	1.600	1.080
Atp6v0a4	KLA  Compactin  Compactin+KLA	NM_080467	ATPase, H+ transporting, lysosomal V0 subunit A4 (Atp6v0a4), mRNA [NM_080467]	KLA	0.980	0.980	1.090	0.980	1.020	0.980	1.090
				Compactin	0.940	1.030	0.990	0.960	0.960	1.080	0.990
				KLA/Compactin	1.020	1.010	1.000	0.950	1.030	1.030	1.020
Atp6v0a4	KLA  Compactin  Compactin+KLA	NM_080467	ATPase, H+ transporting, lysosomal V0 subunit A4 (Atp6v0a4), mRNA [NM_080467]	KLA	1.020	0.950	1.030	1.060	1.020	1.010	1.010
				Compactin	1.060	0.940	1.010	1.030	1.000	0.980	0.990
				KLA/Compactin	0.960	0.970	0.980	0.980	1.020	1.020	1.030
Atp6v0c	KLA  Compactin  Compactin+KLA	NM_009729	ATPase, H+ transporting, lysosomal V0 subunit C (Atp6v0c), mRNA [NM_009729]	KLA	1.100	1.100	1.130	1.140	1.330	1.320	1.580
				Compactin	1.110	0.990	1.040	1.180	0.880	0.880	0.810
				KLA/Compactin	1.200	1.050	1.050	1.230	1.020	1.110	1.540
Atp6v0d1	KLA  Compactin  Compactin+KLA	NM_013477	ATPase, H+ transporting, lysosomal V0 subunit D1 (Atp6v0d1), mRNA [NM_013477]	KLA	0.800	0.960	0.710	1.070	1.660	1.450	1.260
				Compactin	0.920	1.000	0.910	0.990	1.010	1.120	0.910
				KLA/Compactin	1.050	0.970	0.830	1.080	1.240	1.430	1.680
Atp6v0d2	KLA  Compactin  Compactin+KLA	NM_175406	ATPase, H+ transporting, lysosomal V0 subunit D2 (Atp6v0d2), mRNA [NM_175406]	KLA	0.950	1.040	0.900	0.880	0.870	0.790	0.610
				Compactin	1.030	1.090	1.010	1.000	0.910	0.860	0.690
				KLA/Compactin	0.920	0.920	0.970	0.890	0.820	0.690	0.550
Atp6v0e	KLA  Compactin  Compactin+KLA	AK134836	adult male medulla oblongata cDNA, RIKEN full-length enriched library, clone:6330589P19 product:ATPase, H+ transporting, V0 subunit, full insert sequence. [AK134836]	KLA	0.830	0.760	0.780	0.670	1.540	1.590	1.960
				Compactin	0.800	0.980	0.880	0.760	1.080	0.900	1.140
				KLA/Compactin	0.800	0.740	0.820	0.670	1.330	1.250	1.970
Atp6v0e	KLA  Compactin  Compactin+KLA	NM_025272	ATPase, H+ transporting, lysosomal V0 subunit E (Atp6v0e), mRNA [NM_025272]	KLA	1.080	0.940	1.040	1.030	1.440	1.220	1.370
				Compactin	1.040	1.160	1.120	1.150	1.040	1.150	0.920
				KLA/Compactin	0.990	1.090	1.050	1.030	1.070	1.240	1.270
Atp6v0e2	KLA  Compactin  Compactin+KLA	NM_133764	ATPase, H+ transporting, lysosomal V0 subunit E2 (Atp6v0e2), mRNA [NM_133764]	KLA	0.860	0.740	0.660	0.630	0.530	0.520	0.710
				Compactin	0.830	0.880	0.810	0.730	1.020	0.920	0.700
				KLA/Compactin	0.800	0.830	0.640	0.560	0.470	0.570	0.730
Atp6v0e2	KLA  Compactin  Compactin+KLA	NM_133764	ATPase, H+ transporting, lysosomal V0 subunit E2 (Atp6v0e2), mRNA [NM_133764]	KLA	0.930	0.900	0.840	0.800	0.630	0.710	0.910
				Compactin	1.030	0.970	0.980	0.960	1.050	1.030	0.850
				KLA/Compactin	0.900	0.920	0.800	0.690	0.610	0.620	0.860
Atp6v1a	KLA  Compactin  Compactin+KLA	NM_007508	ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a), mRNA [NM_007508]	KLA	1.070	0.920	0.970	0.730	1.040	1.120	1.130
				Compactin	1.030	1.070	1.110	1.040	0.840	0.710	0.550
				KLA/Compactin	1.120	0.950	0.920	0.810	0.760	1.090	0.930
Atp6v1a	KLA  Compactin  Compactin+KLA	NM_007508	ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a), mRNA [NM_007508]	KLA	1.160	0.960	0.960	0.820	1.020	1.160	0.930
				Compactin	1.050	1.030	1.060	1.070	0.890	0.600	0.520
				KLA/Compactin	1.150	0.920	0.940	0.860	0.980	0.860	0.790
Atp6v1b1	KLA  Compactin  Compactin+KLA	NM_134157	ATPase, H+ transporting, lysosomal V1 subunit B1 (Atp6v1b1), mRNA [NM_134157]	KLA	1.010	0.960	0.980	1.010	1.040	0.980	1.010
				Compactin	1.070	0.950	1.030	0.950	0.980	1.000	0.930
				KLA/Compactin	0.920	1.070	0.990	1.020	1.060	0.960	0.960
Atp6v1b2	KLA  Compactin  Compactin+KLA	NM_007509	ATPase, H+ transporting, lysosomal V1 subunit B2 (Atp6v1b2), mRNA [NM_007509]	KLA	1.100	0.900	1.030	1.300	1.590	1.400	1.390
				Compactin	1.070	1.160	1.090	1.130	0.880	0.980	0.940
				KLA/Compactin	1.160	1.020	1.030	1.270	1.570	1.220	1.440
Atp6v1c1	KLA  Compactin  Compactin+KLA	NM_025494	ATPase, H+ transporting, lysosomal V1 subunit C1 (Atp6v1c1), mRNA [NM_025494]	KLA	1.000	0.910	0.980	0.920	0.870	0.900	0.890
				Compactin	1.010	1.080	0.950	1.020	0.810	0.710	0.510
				KLA/Compactin	0.960	0.980	0.870	0.760	0.790	0.950	0.760
Atp6v1c2	KLA  Compactin  Compactin+KLA	NM_133699	ATPase, H+ transporting, lysosomal V1 subunit C2 (Atp6v1c2), mRNA [NM_133699]	KLA	1.080	1.010	0.990	1.020	1.000	0.980	0.980
				Compactin	0.990	1.020	1.040	1.010	0.970	0.950	1.030
				KLA/Compactin	1.030	0.980	0.970	1.000	0.990	1.010	0.970
Atp6v1d	KLA  Compactin  Compactin+KLA	NM_023721	ATPase, H+ transporting, lysosomal V1 subunit D (Atp6v1d), mRNA [NM_023721]	KLA	1.070	1.140	1.130	1.290	1.430	1.820	1.640
				Compactin	1.070	1.290	1.080	1.330	0.880	0.900	0.770
				KLA/Compactin	1.200	1.090	1.110	1.210	1.260	1.740	1.310
Atp6v1e1	KLA  Compactin  Compactin+KLA	NM_007510	VATPase, H+ transporting, lysosomal V1 subunit E1 (Atp6v1e1), mRNA [NM_007510]	KLA	0.910	1.010	1.020	1.470	1.440	1.440	1.580
				Compactin	0.960	0.770	0.800	0.890	0.990	0.940	0.970
				KLA/Compactin	0.930	0.980	1.000	1.240	1.400	1.410	1.960
Atp6v1e1	KLA  Compactin  Compactin+KLA	NM_007510	VATPase, H+ transporting, lysosomal V1 subunit E1 (Atp6v1e1), mRNA [NM_007510]	KLA	0.960	1.060	1.120	1.670	1.550	1.670	2.110
				Compactin	1.150	1.010	0.940	1.030	0.950	1.050	1.050
				KLA/Compactin	0.980	1.000	1.090	1.510	1.710	1.700	1.820
Atp6v1e2	KLA  Compactin  Compactin+KLA	NM_029121	ATPase, H+ transporting, lysosomal V1 subunit E2 (Atp6v1e2), mRNA [NM_029121]	KLA	1.050	0.930	1.000	1.110	0.970	0.980	1.040
				Compactin	0.930	0.970	0.930	0.950	1.090	1.000	0.920
				KLA/Compactin	0.900	1.050	0.980	0.980	0.980	1.010	1.080
Atp6v1f	KLA  Compactin  Compactin+KLA	NM_025381	ATPase, H+ transporting, lysosomal V1 subunit F (Atp6v1f), mRNA [NM_025381]	KLA	1.190	0.970	1.080	1.140	1.000	1.030	1.100
				Compactin	1.140	1.110	1.090	1.010	1.230	1.020	0.790
				KLA/Compactin	1.140	1.040	1.150	1.250	1.070	1.070	0.950
Atp6v1f	KLA  Compactin  Compactin+KLA	NM_025381	ATPase, H+ transporting, lysosomal V1 subunit F (Atp6v1f), mRNA [NM_025381]	KLA	1.320	1.100	1.230	1.410	1.250	1.330	1.300
				Compactin	1.150	1.290	1.100	1.280	1.210	0.900	0.860
				KLA/Compactin	1.090	1.120	1.090	1.280	1.350	1.090	1.030
Atp6v1g1	KLA  Compactin  Compactin+KLA	NM_024173	ATPase, H+ transporting, lysosomal V1 subunit G1 (Atp6v1g1), mRNA [NM_024173]	KLA	0.860	0.880	0.750	0.980	1.290	1.350	1.390
				Compactin	0.860	0.870	0.840	0.790	0.980	0.900	0.930
				KLA/Compactin	0.830	0.810	0.910	0.900	1.150	1.340	1.620
Atp6v1g1	KLA  Compactin  Compactin+KLA	NM_024173	ATPase, H+ transporting, lysosomal V1 subunit G1 (Atp6v1g1), mRNA [NM_024173]	KLA	0.960	1.030	0.930	1.090	1.200	1.280	1.040
				Compactin	1.060	1.220	1.260	1.220	0.890	0.940	0.930
				KLA/Compactin	1.010	0.970	1.110	1.300	1.230	1.500	1.190
Atp6v1g2	KLA  Compactin  Compactin+KLA	NM_023179	ATPase, H+ transporting, lysosomal V1 subunit G2 (Atp6v1g2), mRNA [NM_023179]	KLA	1.000	1.010	1.060	1.070	1.030	1.010	1.050
				Compactin	1.000	1.060	1.010	0.950	1.000	0.990	1.140
				KLA/Compactin	0.940	0.970	1.050	1.050	1.080	1.020	1.060
Atp6v1g2	KLA  Compactin  Compactin+KLA	NM_023179	ATPase, H+ transporting, lysosomal V1 subunit G2 (Atp6v1g2), mRNA [NM_023179]	KLA	1.010	1.040	1.070	1.280	1.160	1.140	1.330
				Compactin	0.980	0.930	0.990	1.060	1.100	1.040	0.990
				KLA/Compactin	0.960	1.030	1.050	1.110	1.250	1.150	1.310
Atp6v1g3	KLA  Compactin  Compactin+KLA	NM_177397	ATPase, H+ transporting, lysosomal V1 subunit G3 (Atp6v1g3), mRNA [NM_177397]	KLA	0.980	1.060	1.000	0.990	1.020	1.010	0.970
				Compactin	1.020	1.090	1.050	1.010	1.040	0.970	1.000
				KLA/Compactin	0.990	1.020	0.990	1.000	0.980	1.010	1.010
Atp6v1g3	KLA  Compactin  Compactin+KLA	NM_177397	ATPase, H+ transporting, lysosomal V1 subunit G3 (Atp6v1g3), mRNA [NM_177397]	KLA	0.990	1.020	1.020	1.050	0.990	1.030	1.070
				Compactin	0.990	1.010	1.000	0.990	0.980	0.980	0.960
				KLA/Compactin	1.010	0.960	0.990	0.990	0.960	1.020	1.040
Atp6v1g3	KLA  Compactin  Compactin+KLA	NM_177397	ATPase, H+ transporting, lysosomal V1 subunit G3 (Atp6v1g3), mRNA [NM_177397]	KLA	1.020	0.980	0.970	0.960	1.010	1.060	0.960
				Compactin	1.090	1.040	1.020	1.030	1.050	0.960	0.940
				KLA/Compactin	1.030	0.970	0.970	1.020	1.030	1.110	0.960
Car2	KLA  Compactin  Compactin+KLA	NM_009801	carbonic anhydrase 2 (Car2), mRNA [NM_009801]	KLA	1.070	1.180	1.320	1.520	1.020	0.690	1.510
				Compactin	1.110	1.140	1.080	1.120	1.050	1.010	1.700
				KLA/Compactin	0.940	1.440	1.400	1.430	0.980	0.820	1.410
Clcnkb	KLA  Compactin  Compactin+KLA	172072654	chloride channel Kb	KLA	1.170	0.900	1.110	1.040	1.170	1.010	0.740
				Compactin	1.040	1.020	0.960	0.960	1.000	0.920	1.080
				KLA/Compactin	1.100	0.820	1.030	1.090	0.950	0.890	0.750
Clcnkb	KLA  Compactin  Compactin+KLA	BC019983	chloride channel Kb, mRNA (cDNA clone MGC:28502 IMAGE:4188062), complete cds [BC019983]	KLA	1.060	1.010	1.360	0.950	0.990	1.010	1.020
				Compactin	1.090	0.960	1.030	1.040	1.040	0.950	0.960
				KLA/Compactin	0.970	1.010	1.020	1.040	1.000	1.090	1.070
Slc12a7	KLA  Compactin  Compactin+KLA	NM_011390	solute carrier family 12, member 7 (Slc12a7), mRNA [NM_011390]	KLA	1.060	0.890	0.890	1.310	1.340	1.410	1.310
				Compactin	1.000	0.990	0.940	0.870	0.990	1.130	1.070
				KLA/Compactin	1.070	1.070	0.760	1.050	1.520	1.310	1.370
Slc4a1	KLA  Compactin  Compactin+KLA	6755559	solute carrier family 4 (anion exchanger), member 1	KLA	1.060	1.010	1.060	1.020	1.020	1.010	0.960
				Compactin	1.090	0.980	1.010	1.040	1.080	0.980	0.980
				KLA/Compactin	0.970	1.040	1.030	1.000	0.950	0.990	1.000
Slc4a1	KLA  Compactin  Compactin+KLA	NM_011403	solute carrier family 4 (anion exchanger), member 1 (Slc4a1), mRNA [NM_011403]	KLA	1.120	1.000	0.950	1.030	0.990	1.020	1.050
				Compactin	0.980	0.980	1.080	1.040	0.970	0.960	0.940
				KLA/Compactin	0.990	1.060	1.010	1.050	1.000	1.040	1.050
Tcirg1	KLA  Compactin  Compactin+KLA	NM_016921	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 (Tcirg1), mRNA [NM_016921]	KLA	1.060	1.000	1.330	1.600	1.610	1.830	1.580
				Compactin	1.150	1.080	1.020	1.110	0.830	0.940	0.730
				KLA/Compactin	1.230	1.060	1.200	1.540	1.250	1.540	1.260