Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Phototransduction (mmu04744)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Arrb1
KLA  Compactin  Compactin+KLA
 NM_177231 arrestin, beta 1 (Arrb1), transcript variant a, mRNA [NM_177231] KLA0.920 1.030 0.870 0.640 0.580 0.720 0.740
Compactin0.980 0.970 0.930 0.850 1.080 1.380 0.960
KLA/Compactin0.810 1.050 1.070 0.670 0.620 0.650 0.830
Arrb1
KLA  Compactin  Compactin+KLA
 NM_177231 arrestin, beta 1 (Arrb1), transcript variant a, mRNA [NM_177231] KLA1.340 1.010 0.900 0.370 0.310 0.310 0.230
Compactin1.040 1.310 1.300 1.140 1.080 1.060 0.770
KLA/Compactin1.320 1.020 0.810 0.430 0.300 0.300 0.210
Arrb2
KLA  Compactin  Compactin+KLA
 146149233 arrestin, beta 2 KLA0.980 1.020 1.050 0.960 1.310 1.420 1.050
Compactin1.070 1.040 1.040 1.160 0.970 1.000 1.220
KLA/Compactin1.040 0.950 1.090 1.060 1.330 1.200 1.040
Calm1
KLA  Compactin  Compactin+KLA
 NM_009790 calmodulin 1 (Calm1), mRNA [NM_009790] KLA0.890 0.930 0.970 1.140 1.000 1.130 1.570
Compactin1.020 0.980 1.000 1.030 1.110 1.130 1.350
KLA/Compactin1.010 0.920 1.000 0.990 1.270 1.580 1.550
Calm1
KLA  Compactin  Compactin+KLA
 NM_009790 calmodulin 1 (Calm1), mRNA [NM_009790] KLA1.040 1.110 1.070 1.240 0.900 0.700 0.570
Compactin1.160 1.130 1.050 1.180 1.050 1.180 1.320
KLA/Compactin1.100 1.030 1.040 1.130 0.910 0.740 0.600
Calm1
KLA  Compactin  Compactin+KLA
 NM_009790 calmodulin 1 (Calm1), mRNA [NM_009790] KLA1.070 1.020 1.020 0.960 0.850 0.830 0.700
Compactin1.020 1.080 1.000 1.020 1.040 1.090 1.170
KLA/Compactin1.000 1.020 1.070 0.990 0.870 0.720 0.750
Calm2
KLA  Compactin  Compactin+KLA
 NM_007589 calmodulin 2 (Calm2), mRNA [NM_007589] KLA0.830 0.890 0.910 0.870 0.800 0.750 0.640
Compactin0.880 0.970 0.970 0.870 0.950 1.060 1.240
KLA/Compactin0.860 0.830 0.960 0.900 0.730 0.740 0.620
Calm2
KLA  Compactin  Compactin+KLA
 NM_007589 calmodulin 2 (Calm2), mRNA [NM_007589] KLA1.100 1.090 1.190 0.900 0.650 0.820 0.720
Compactin1.090 1.110 1.160 1.090 1.140 1.010 1.070
KLA/Compactin1.060 0.960 1.090 0.990 0.840 0.660 0.650
Calm3
KLA  Compactin  Compactin+KLA
 NM_007590 calmodulin 3 (Calm3), mRNA [NM_007590] KLA0.880 0.930 0.970 1.050 1.150 1.280 1.660
Compactin0.840 1.010 0.990 0.940 0.940 1.090 1.150
KLA/Compactin0.890 0.910 0.940 1.160 1.080 1.260 1.910
Calm3
KLA  Compactin  Compactin+KLA
 NM_007590 calmodulin 3 (Calm3), mRNA [NM_007590] KLA0.960 1.000 1.070 1.070 0.710 0.770 1.000
Compactin1.020 1.040 1.020 1.140 1.120 1.070 0.990
KLA/Compactin1.010 0.920 0.910 0.930 0.890 1.060 1.120
Calm3
KLA  Compactin  Compactin+KLA
 NM_007590 calmodulin 3 (Calm3), mRNA [NM_007590] KLA1.260 1.230 1.170 1.130 0.920 0.950 1.000
Compactin1.170 1.300 1.350 1.150 0.840 1.090 1.090
KLA/Compactin1.140 1.020 1.160 1.310 1.020 0.880 1.080
Calm4
KLA  Compactin  Compactin+KLA
 NM_020036 calmodulin 4 (Calm4), mRNA [NM_020036] KLA1.000 0.990 1.010 1.030 1.040 1.070 0.970
Compactin0.990 0.950 1.040 0.990 0.940 1.020 0.990
KLA/Compactin0.980 0.990 1.040 1.070 1.000 1.150 0.970
Calm4
KLA  Compactin  Compactin+KLA
 NM_020036 calmodulin 4 (Calm4), mRNA [NM_020036] KLA1.020 0.980 1.030 1.060 1.010 0.960 0.950
Compactin0.960 1.040 1.040 0.990 0.990 1.020 0.990
KLA/Compactin0.940 0.970 1.130 1.030 0.970 1.080 0.980
Calm5
KLA  Compactin  Compactin+KLA
 NM_001008706 calmodulin 5 (Calm5), mRNA [NM_001008706] KLA1.020 1.000 1.030 0.880 1.020 1.060 0.940
Compactin0.890 0.970 1.010 0.970 1.030 1.060 1.010
KLA/Compactin0.980 0.970 1.000 0.960 0.970 0.950 1.020
Calml3
KLA  Compactin  Compactin+KLA
 NM_027416 calmodulin-like 3 (Calml3), mRNA [NM_027416] KLA0.940 1.010 0.960 1.020 0.970 1.020 1.060
Compactin1.010 1.020 1.010 1.010 1.000 0.970 1.050
KLA/Compactin0.980 1.030 1.000 1.080 1.020 1.040 1.020
Cnga1
KLA  Compactin  Compactin+KLA
 U19717 cGMP-gated cation channel mRNA, clone mIMCD-K2 no.1, complete cds. [U19717] KLA1.070 0.990 1.060 1.010 0.980 1.030 0.980
Compactin0.960 0.990 1.000 0.950 0.990 1.010 1.030
KLA/Compactin0.920 0.990 1.000 1.070 1.100 0.950 1.000
Cngb1
KLA  Compactin  Compactin+KLA
 BC045114 cyclic nucleotide gated channel beta 1, mRNA (cDNA clone IMAGE:4504353), partial cds [BC045114] KLA1.040 0.970 0.990 1.020 0.950 0.980 0.960
Compactin1.050 1.020 0.950 0.990 0.880 1.030 0.960
KLA/Compactin0.980 1.000 1.000 0.960 1.040 1.090 1.000
Gnat1
KLA  Compactin  Compactin+KLA
 NM_008140 guanine nucleotide binding protein, alpha transducing 1 (Gnat1), mRNA [NM_008140] KLA0.990 0.910 0.970 1.080 0.990 0.900 1.040
Compactin1.020 0.940 1.020 0.970 1.000 1.040 0.980
KLA/Compactin1.000 1.030 0.980 0.980 1.020 1.050 0.990
Gnat1
KLA  Compactin  Compactin+KLA
 NM_008140 guanine nucleotide binding protein, alpha transducing 1 (Gnat1), mRNA [NM_008140] KLA1.050 1.030 0.970 1.010 0.960 0.950 1.030
Compactin1.020 0.960 1.040 0.980 1.040 1.040 0.940
KLA/Compactin0.980 1.030 1.050 1.000 0.960 0.960 1.000
Gnat2
KLA  Compactin  Compactin+KLA
 NM_008141 guanine nucleotide binding protein, alpha transducing 2 (Gnat2), mRNA [NM_008141] KLA0.980 1.010 0.970 0.930 0.800 0.860 0.770
Compactin1.110 1.000 1.080 1.060 1.040 0.990 1.080
KLA/Compactin1.020 1.110 1.040 1.000 0.820 0.800 0.820
Gnb1
KLA  Compactin  Compactin+KLA
 NM_008142 guanine nucleotide binding protein (G protein), beta 1 (Gnb1), mRNA [NM_008142] KLA0.930 0.920 1.040 1.200 1.010 1.000 0.650
Compactin1.050 0.880 0.910 1.100 1.040 1.050 1.330
KLA/Compactin0.960 0.900 1.000 1.090 1.350 0.940 0.580
Gnb1
KLA  Compactin  Compactin+KLA
 NM_008142 guanine nucleotide binding protein (G protein), beta 1 (Gnb1), mRNA [NM_008142] KLA1.010 1.120 1.140 1.250 1.360 1.800 2.870
Compactin1.170 1.110 1.160 1.230 0.990 1.150 1.500
KLA/Compactin1.100 1.020 1.150 1.290 1.670 1.950 3.230
Gnb1
KLA  Compactin  Compactin+KLA
 NM_008142 guanine nucleotide binding protein (G protein), beta 1 (Gnb1), mRNA [NM_008142] KLA1.040 1.030 1.070 1.260 1.240 1.400 2.660
Compactin0.940 1.110 1.160 1.310 1.090 1.120 1.320
KLA/Compactin1.130 0.980 1.150 1.240 1.800 2.130 2.260
Gnb1
KLA  Compactin  Compactin+KLA
 NM_008142 guanine nucleotide binding protein (G protein), beta 1 (Gnb1), mRNA [NM_008142] KLA1.350 1.220 1.090 1.160 1.440 1.640 2.010
Compactin1.090 1.190 1.320 1.170 1.350 1.010 1.290
KLA/Compactin1.310 1.020 1.230 1.480 1.510 1.790 2.630
Gngt1
KLA  Compactin  Compactin+KLA
 NM_010314 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 (Gngt1), mRNA [NM_010314] KLA0.970 1.000 0.910 1.050 1.020 1.000 1.010
Compactin0.990 1.050 0.950 0.960 0.990 0.990 2.020
KLA/Compactin0.990 1.000 1.000 1.060 1.000 1.070 1.050
Grk1
KLA  Compactin  Compactin+KLA
 NM_011881 G protein-coupled receptor kinase 1 (Grk1), mRNA [NM_011881] KLA0.980 1.020 1.030 1.010 0.990 0.960 0.950
Compactin1.030 0.960 1.010 1.020 1.040 1.030 0.990
KLA/Compactin1.000 1.030 1.010 0.970 1.070 0.980 1.020
Guca1a
KLA  Compactin  Compactin+KLA
 NM_008189 guanylate cyclase activator 1a (retina) (Guca1a), mRNA [NM_008189] KLA1.130 1.080 1.070 1.070 0.820 0.960 1.650
Compactin1.170 1.090 1.190 1.200 1.130 1.060 0.880
KLA/Compactin0.990 0.990 0.970 1.180 0.890 0.920 1.510
Guca1b
KLA  Compactin  Compactin+KLA
 NM_146079 guanylate cyclase activator 1B (Guca1b), mRNA [NM_146079] KLA0.930 0.950 1.100 1.280 1.390 1.110 1.270
Compactin0.810 0.870 0.850 0.880 1.080 1.030 0.960
KLA/Compactin0.950 1.000 0.980 1.130 1.130 1.320 1.530
Gucy2e
KLA  Compactin  Compactin+KLA
 BC057954 guanylate cyclase 2e, mRNA (cDNA clone MGC:68216 IMAGE:5360206), complete cds. [BC057954] KLA0.990 1.000 0.990 0.970 1.040 0.960 1.010
Compactin1.070 1.050 0.990 1.030 1.000 0.980 1.020
KLA/Compactin0.990 1.050 0.990 0.950 1.000 0.990 1.020
Gucy2e
KLA  Compactin  Compactin+KLA
 NM_008192 guanylate cyclase 2e (Gucy2e), mRNA [NM_008192] KLA0.970 1.010 1.020 1.020 1.000 0.930 1.020
Compactin0.990 1.040 1.080 0.980 0.980 0.950 0.980
KLA/Compactin0.980 1.040 1.000 0.940 0.950 0.990 1.010
Gucy2e
KLA  Compactin  Compactin+KLA
 NM_008192 guanylate cyclase 2e (Gucy2e), mRNA [NM_008192] KLA1.040 1.020 1.080 0.940 0.990 0.970 0.960
Compactin0.970 1.050 1.000 1.070 0.980 1.000 1.010
KLA/Compactin1.010 0.960 0.940 1.010 1.100 1.020 0.960
Gucy2f
KLA  Compactin  Compactin+KLA
 NM_001007576 guanylate cyclase 2f (Gucy2f), mRNA [NM_001007576] KLA1.060 0.890 1.000 1.020 1.030 0.870 0.940
Compactin1.030 0.910 1.060 0.940 0.990 1.060 0.960
KLA/Compactin0.980 1.040 1.020 1.000 0.940 1.100 0.980
Pde6a
KLA  Compactin  Compactin+KLA
 NM_146086 phosphodiesterase 6A, cGMP-specific, rod, alpha (Pde6a), mRNA [NM_146086] KLA0.980 0.990 1.070 0.980 0.980 1.010 0.990
Compactin0.980 1.030 1.010 0.980 0.960 1.020 1.010
KLA/Compactin1.000 1.010 1.080 0.960 1.000 1.030 1.050
Pde6b
KLA  Compactin  Compactin+KLA
 NM_008806 phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide (Pde6b), mRNA [NM_008806] KLA0.990 0.960 0.950 0.990 1.020 1.090 1.010
Compactin1.030 0.930 0.960 1.000 0.960 0.980 0.960
KLA/Compactin1.000 1.010 1.020 0.940 0.950 0.960 1.000
Pde6g
KLA  Compactin  Compactin+KLA
 NM_012065 phosphodiesterase 6G, cGMP-specific, rod, gamma (Pde6g), mRNA [NM_012065] KLA0.990 0.960 0.950 1.030 0.940 0.980 1.070
Compactin0.910 0.970 0.970 1.060 1.040 1.000 0.980
KLA/Compactin0.990 1.020 0.930 1.000 1.080 1.180 1.030
Rcvrn
KLA  Compactin  Compactin+KLA
 162951841 recoverin KLA1.090 1.580 0.970 1.000 0.990 0.900 0.940
Compactin1.070 0.940 1.050 1.030 1.050 0.990 1.160
KLA/Compactin0.990 1.360 1.080 1.040 1.000 1.040 1.040
Rcvrn
KLA  Compactin  Compactin+KLA
 X66196 gb|M.musculus mRNA for 23 kDa photoreceptor cell-specific protein. [X66196] KLA1.100 1.530 1.080 0.970 1.030 0.990 0.970
Compactin1.050 1.000 1.000 1.010 1.030 1.030 1.070
KLA/Compactin0.980 1.510 1.030 1.030 1.120 0.900 0.940
Rgs9
KLA  Compactin  Compactin+KLA
 NM_011268 regulator of G-protein signaling 9 (Rgs9), mRNA [NM_011268] KLA0.900 0.990 1.010 1.070 0.930 1.020 1.070
Compactin1.010 0.940 0.930 1.020 0.900 0.920 0.970
KLA/Compactin0.920 1.020 1.030 1.000 0.930 0.990 0.940
Rho
KLA  Compactin  Compactin+KLA
 21717804 rhodopsin KLA1.060 1.020 0.980 0.930 1.050 1.070 0.980
Compactin1.020 0.950 0.980 1.010 0.910 1.030 1.070
KLA/Compactin1.020 0.960 1.020 1.050 1.030 0.990 1.030
Rho
KLA  Compactin  Compactin+KLA
 NM_145383 rhodopsin (Rho), mRNA [NM_145383] KLA1.030 0.970 1.010 1.030 0.970 0.980 1.120
Compactin1.020 0.990 0.960 1.000 0.940 0.980 0.990
KLA/Compactin1.050 0.970 1.050 1.070 0.980 0.950 0.980
Slc24a1
KLA  Compactin  Compactin+KLA
 NM_144813 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 (Slc24a1), mRNA [NM_144813] KLA0.960 0.930 0.930 1.000 1.030 1.040 1.040
Compactin1.050 1.030 1.050 0.990 1.030 0.960 1.040
KLA/Compactin1.010 0.980 0.980 1.020 1.100 1.030 1.060