Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Homologous recombination (mmu03440)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
AK085134
KLA  Compactin  Compactin+KLA
 AK085134 13 days embryo lung cDNA, RIKEN full-length enriched library, clone:D430042D16 product:unclassifiable, full insert sequence. [AK085134] KLA1.030 1.100 1.140 1.010 1.000 0.960 0.990
Compactin0.980 1.010 1.030 1.030 1.010 0.970 0.980
KLA/Compactin1.110 1.070 1.110 1.050 0.960 0.980 0.960
AK085134
KLA  Compactin  Compactin+KLA
 AK085134 13 days embryo lung cDNA, RIKEN full-length enriched library, clone:D430042D16 product:unclassifiable, full insert sequence. [AK085134] KLA1.030 1.130 1.180 1.050 1.030 0.970 0.950
Compactin1.020 1.010 0.970 1.030 0.930 1.040 1.070
KLA/Compactin1.120 1.240 1.090 1.120 1.010 0.920 0.890
Blm
KLA  Compactin  Compactin+KLA
 NM_007550 Bloom syndrome homolog (human) (Blm), transcript variant 1, mRNA [NM_007550] KLA1.100 1.140 1.070 0.690 0.600 0.630 1.090
Compactin1.140 1.000 1.150 1.160 0.920 1.010 0.730
KLA/Compactin1.200 1.230 1.050 0.840 0.590 0.650 1.150
Brca2
KLA  Compactin  Compactin+KLA
 124487408 breast cancer 2 KLA1.210 1.100 0.940 0.530 0.370 0.340 0.290
Compactin1.140 1.160 1.080 1.100 1.030 0.910 0.810
KLA/Compactin1.310 1.200 0.960 0.600 0.380 0.320 0.240
Brca2
KLA  Compactin  Compactin+KLA
 NM_009765 breast cancer 2 (Brca2), transcript variant 2, mRNA [NM_009765] KLA1.080 1.100 0.960 0.520 0.380 0.370 0.270
Compactin0.980 1.020 1.110 1.000 0.920 0.870 0.860
KLA/Compactin1.110 1.030 0.980 0.600 0.400 0.310 0.260
E130016E
03Rik
KLA  Compactin  Compactin+KLA
 AK147819 melanocyte cDNA, RIKEN full-length enriched library, clone:G270053E10 product:Fibrinogen silencer binding protein homolog, full insert sequence [AK147819] KLA1.020 0.970 0.970 0.890 0.760 0.790 0.860
Compactin1.030 1.060 1.060 1.010 0.960 0.930 0.870
KLA/Compactin1.000 1.070 0.920 0.880 0.800 0.760 0.850
E130016E
03Rik
KLA  Compactin  Compactin+KLA
 NM_001039556 RIKEN cDNA E130016E03 gene (E130016E03Rik), mRNA [NM_001039556] KLA0.840 0.880 0.650 0.520 0.490 0.510 0.600
Compactin0.880 0.880 0.840 0.720 0.980 1.210 0.770
KLA/Compactin0.820 0.970 0.630 0.580 0.370 0.450 0.490
E130016E
03Rik
KLA  Compactin  Compactin+KLA
 NM_001039556 RIKEN cDNA E130016E03 gene (E130016E03Rik), mRNA [NM_001039556] KLA0.950 0.960 0.870 0.950 0.840 0.800 0.870
Compactin1.020 1.040 0.940 1.040 0.890 1.020 0.930
KLA/Compactin0.990 1.000 0.950 0.920 0.830 0.870 0.940
E130016E
03Rik
KLA  Compactin  Compactin+KLA
 NM_001039556 RIKEN cDNA E130016E03 gene (E130016E03Rik), mRNA [NM_001039556] KLA0.960 1.000 0.920 0.810 0.800 0.820 0.940
Compactin0.940 1.060 0.960 0.980 0.950 0.980 0.990
KLA/Compactin1.090 0.970 0.960 0.910 0.870 0.790 0.910
Eme1
KLA  Compactin  Compactin+KLA
 NM_177752 essential meiotic endonuclease 1 homolog 1 (S. pombe) (Eme1), mRNA [NM_177752] KLA0.980 0.910 0.940 0.980 0.630 0.550 0.670
Compactin1.010 1.070 0.980 1.000 1.000 0.980 0.780
KLA/Compactin0.950 0.910 0.850 0.920 0.650 0.580 0.640
Mre11a
KLA  Compactin  Compactin+KLA
 AK161013 15 days embryo head cDNA, RIKEN full-length enriched library, clone:4022449A05 product:meiotic recombination 11 homolog A (S. cerevisiae), full insert sequence [AK161013] KLA1.010 0.790 0.810 0.730 0.740 0.730 0.910
Compactin0.930 1.010 0.960 0.990 0.940 0.860 0.840
KLA/Compactin0.970 0.810 0.820 0.750 0.680 0.700 0.870
Mre11a
KLA  Compactin  Compactin+KLA
 AK161013 15 days embryo head cDNA, RIKEN full-length enriched library, clone:4022449A05 product:meiotic recombination 11 homolog A (S. cerevisiae), full insert sequence [AK161013] KLA1.070 0.790 0.850 0.790 0.680 0.730 0.880
Compactin1.030 1.030 0.940 0.950 0.900 0.840 0.800
KLA/Compactin1.020 0.770 0.830 0.740 0.690 0.690 0.910
Mre11a
KLA  Compactin  Compactin+KLA
 NM_018736 meiotic recombination 11 homolog A (S. cerevisiae) (Mre11a), mRNA [NM_018736] KLA0.820 0.910 0.950 1.100 0.880 0.740 1.370
Compactin0.900 0.850 0.810 0.760 1.100 1.040 0.880
KLA/Compactin0.910 0.950 0.890 0.980 0.690 0.900 1.610
Mre11a
KLA  Compactin  Compactin+KLA
 NM_018736 meiotic recombination 11 homolog A (S. cerevisiae) (Mre11a), mRNA [NM_018736] KLA0.830 0.930 1.010 1.000 0.840 0.840 1.320
Compactin0.950 0.840 0.990 0.950 0.960 1.050 0.980
KLA/Compactin0.900 1.050 1.000 0.980 0.950 0.880 1.180
Mre11a
KLA  Compactin  Compactin+KLA
 NM_018736 meiotic recombination 11 homolog A (S. cerevisiae) (Mre11a), mRNA [NM_018736] KLA0.920 0.980 0.860 0.970 0.820 0.780 1.080
Compactin0.900 0.940 1.060 0.930 0.950 0.970 0.870
KLA/Compactin0.950 0.970 1.000 0.920 0.780 0.800 1.060
Mus81
KLA  Compactin  Compactin+KLA
 NM_027877 MUS81 endonuclease homolog (yeast) (Mus81), mRNA [NM_027877] KLA0.950 0.990 0.990 1.070 1.130 1.240 1.410
Compactin0.870 1.020 1.040 0.840 0.900 0.950 1.110
KLA/Compactin0.910 0.970 1.040 1.050 0.980 1.110 1.340
Mus81
KLA  Compactin  Compactin+KLA
 NM_027877 MUS81 endonuclease homolog (yeast) (Mus81), mRNA [NM_027877] KLA1.090 1.190 1.050 1.140 1.110 1.250 1.450
Compactin1.050 1.090 1.080 0.940 0.960 1.010 1.070
KLA/Compactin1.030 1.070 1.050 1.010 0.950 1.180 1.420
Nbn
KLA  Compactin  Compactin+KLA
 NM_013752 nibrin (Nbn), mRNA [NM_013752] KLA1.000 1.040 1.110 1.000 0.780 0.800 0.740
Compactin1.050 0.990 1.060 1.030 0.890 0.940 0.820
KLA/Compactin0.990 1.050 1.120 0.930 0.710 0.680 0.800
Nbn
KLA  Compactin  Compactin+KLA
 NM_013752 nibrin (Nbn), mRNA [NM_013752] KLA1.130 1.210 1.090 0.930 0.780 0.730 0.590
Compactin1.080 1.110 1.250 1.110 1.020 0.880 0.760
KLA/Compactin1.090 1.100 1.190 0.980 0.710 0.540 0.640
Pold1
KLA  Compactin  Compactin+KLA
 NM_011131 polymerase (DNA directed), delta 1, catalytic subunit (Pold1), mRNA [NM_011131] KLA0.730 0.890 0.640 0.430 0.410 0.340 0.380
Compactin0.850 1.010 0.940 0.760 0.940 1.020 0.700
KLA/Compactin0.910 1.020 0.780 0.380 0.330 0.440 0.540
Pold1
KLA  Compactin  Compactin+KLA
 NM_011131 polymerase (DNA directed), delta 1, catalytic subunit (Pold1), mRNA [NM_011131] KLA0.820 0.790 0.680 0.420 0.400 0.340 0.560
Compactin0.880 0.930 0.770 0.720 1.050 1.010 0.640
KLA/Compactin0.930 0.880 0.630 0.350 0.340 0.450 0.420
Pold1
KLA  Compactin  Compactin+KLA
 NM_011131 polymerase (DNA directed), delta 1, catalytic subunit (Pold1), mRNA [NM_011131] KLA1.000 0.950 0.830 0.460 0.350 0.440 0.500
Compactin1.020 0.900 0.970 1.020 0.930 1.000 0.760
KLA/Compactin1.010 0.970 0.720 0.460 0.420 0.470 0.500
Pold2
KLA  Compactin  Compactin+KLA
 NM_008894 polymerase (DNA directed), delta 2, regulatory subunit (Pold2), mRNA [NM_008894] KLA0.960 0.960 0.920 0.750 0.810 0.710 0.750
Compactin0.920 0.970 1.010 0.860 0.980 0.950 0.920
KLA/Compactin0.850 0.930 0.990 0.780 0.590 0.600 0.880
Pold2
KLA  Compactin  Compactin+KLA
 NM_008894 polymerase (DNA directed), delta 2, regulatory subunit (Pold2), mRNA [NM_008894] KLA1.490 1.070 1.290 1.130 0.760 0.760 0.890
Compactin1.160 1.200 1.180 1.350 1.290 0.950 0.810
KLA/Compactin1.180 1.140 1.220 1.060 0.760 0.640 0.820
Pold3
KLA  Compactin  Compactin+KLA
 NM_133692 polymerase (DNA-directed), delta 3, accessory subunit (Pold3), mRNA [NM_133692] KLA0.870 1.050 0.900 1.140 1.120 1.220 1.860
Compactin0.900 0.880 0.970 0.840 1.040 1.220 0.970
KLA/Compactin0.970 1.060 1.040 1.010 0.950 1.500 1.900
Pold3
KLA  Compactin  Compactin+KLA
 NM_133692 polymerase (DNA-directed), delta 3, accessory subunit (Pold3), mRNA [NM_133692] KLA1.120 1.010 0.930 0.820 0.680 0.680 0.690
Compactin1.240 1.090 1.070 0.900 0.930 0.940 0.800
KLA/Compactin1.000 1.350 1.000 0.900 0.660 0.790 0.750
Pold3
KLA  Compactin  Compactin+KLA
 NM_133692 polymerase (DNA-directed), delta 3, accessory subunit (Pold3), mRNA [NM_133692] KLA1.400 1.180 1.190 1.270 1.070 1.430 2.060
Compactin1.110 1.100 1.090 1.230 1.080 0.930 0.890
KLA/Compactin1.110 1.080 1.170 1.270 1.120 1.260 1.960
Pold4
KLA  Compactin  Compactin+KLA
 NM_027196 polymerase (DNA-directed), delta 4 (Pold4), mRNA [NM_027196] KLA1.110 1.170 1.190 1.270 1.260 1.360 1.600
Compactin1.270 1.060 1.110 1.200 1.170 1.120 1.370
KLA/Compactin1.100 1.050 1.160 1.340 1.480 1.520 2.040
Rad50
KLA  Compactin  Compactin+KLA
 BC002033 RAD50 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:3491597), complete cds. [BC002033] KLA1.080 1.020 0.950 0.980 0.960 0.970 0.920
Compactin1.070 1.090 1.060 0.970 1.100 1.050 0.950
KLA/Compactin1.010 1.030 1.000 0.940 0.950 0.950 1.020
Rad50
KLA  Compactin  Compactin+KLA
 NM_009012 RAD50 homolog (S. cerevisiae) (Rad50), mRNA [NM_009012] KLA1.240 1.130 0.970 0.690 0.710 0.660 0.730
Compactin1.380 1.120 1.130 1.180 1.140 1.050 0.840
KLA/Compactin1.400 1.090 0.940 0.760 0.730 0.710 0.770
Rad51
KLA  Compactin  Compactin+KLA
 NM_011234 RAD51 homolog (S. cerevisiae) (Rad51), mRNA [NM_011234] KLA0.930 0.880 0.790 0.580 0.350 0.380 0.270
Compactin0.930 0.990 0.870 0.920 0.910 0.880 0.640
KLA/Compactin0.860 1.060 0.850 0.550 0.410 0.320 0.200
Rad51c
KLA  Compactin  Compactin+KLA
 NM_053269 Rad51 homolog c (S. cerevisiae) (Rad51c), mRNA [NM_053269] KLA1.100 1.050 0.920 0.690 0.790 1.000 1.260
Compactin1.180 0.980 1.080 1.190 0.970 0.940 0.980
KLA/Compactin1.140 1.130 1.000 0.720 0.790 1.080 1.380
Rad51l1
KLA  Compactin  Compactin+KLA
 NM_009014 RAD51-like 1 (S. cerevisiae) (Rad51l1), mRNA [NM_009014] KLA0.950 1.110 1.180 0.990 0.640 0.510 0.660
Compactin1.030 1.030 1.040 1.140 0.950 0.890 0.770
KLA/Compactin0.970 1.040 1.040 1.010 0.660 0.520 0.600
Rad51l1
KLA  Compactin  Compactin+KLA
 NM_009014 RAD51-like 1 (S. cerevisiae) (Rad51l1), mRNA [NM_009014] KLA0.960 1.060 1.020 0.940 0.780 0.620 0.760
Compactin1.020 1.090 0.980 0.980 0.940 0.980 0.760
KLA/Compactin0.990 1.000 1.060 0.980 0.740 0.690 0.780
Rad51l3
KLA  Compactin  Compactin+KLA
 NM_011235 RAD51-like 3 (S. cerevisiae) (Rad51l3), mRNA [NM_011235] KLA1.020 1.030 0.910 0.970 0.900 1.070 1.360
Compactin1.150 1.140 1.180 1.220 1.030 1.090 0.980
KLA/Compactin1.030 1.080 0.970 1.040 0.940 1.080 1.520
Rad51l3
KLA  Compactin  Compactin+KLA
 NM_011235 RAD51-like 3 (S. cerevisiae) (Rad51l3), mRNA [NM_011235] KLA1.120 0.890 0.860 0.810 0.910 0.890 0.930
Compactin0.910 1.050 0.980 1.020 1.110 1.030 1.080
KLA/Compactin1.000 0.930 0.870 0.880 0.870 0.900 0.900
Rad51l3
KLA  Compactin  Compactin+KLA
 NM_011235 RAD51-like 3 (S. cerevisiae) (Rad51l3), mRNA [NM_011235] KLA1.130 0.880 0.910 0.940 0.900 0.890 0.900
Compactin1.010 1.110 0.940 0.990 1.130 1.100 1.010
KLA/Compactin0.970 0.910 0.880 0.930 0.850 0.920 0.950
Rad52
KLA  Compactin  Compactin+KLA
 NM_011236 RAD52 homolog (S. cerevisiae) (Rad52), mRNA [NM_011236] KLA0.860 0.930 1.060 0.920 1.080 1.210 1.300
Compactin0.860 1.000 0.940 1.040 1.100 1.030 1.210
KLA/Compactin0.940 0.930 0.990 1.030 1.190 1.280 1.360
Rad52
KLA  Compactin  Compactin+KLA
 NM_011236 RAD52 homolog (S. cerevisiae) (Rad52), mRNA [NM_011236] KLA1.000 1.050 1.120 1.050 1.050 1.170 1.350
Compactin0.980 1.040 1.020 1.040 1.210 1.020 1.060
KLA/Compactin1.100 1.050 0.990 1.090 1.290 1.580 1.210
Rad54l
KLA  Compactin  Compactin+KLA
 AK017045 adult male testis cDNA, RIKEN full-length enriched library, clone:4933433M02 product:RAD54 like (S. cerevisiae), full insert sequence. [AK017045] KLA1.000 1.000 0.970 0.920 1.000 1.030 1.000
Compactin0.990 1.040 1.050 0.980 0.920 0.990 1.020
KLA/Compactin0.960 0.900 0.970 1.090 0.960 0.950 1.000
Rad54l
KLA  Compactin  Compactin+KLA
 NM_009015 RAD54 like (S. cerevisiae) (Rad54l), transcript variant 1, mRNA [NM_009015] KLA1.470 1.100 0.990 0.550 0.410 0.360 0.210
Compactin1.060 1.180 1.280 1.300 0.990 1.080 0.540
KLA/Compactin1.210 1.030 1.100 0.550 0.370 0.250 0.200
Rpa1
KLA  Compactin  Compactin+KLA
 NM_026653 replication protein A1 (Rpa1), mRNA [NM_026653] KLA0.720 0.810 0.650 0.540 0.440 0.350 0.470
Compactin0.810 0.880 0.840 0.820 0.890 0.950 0.700
KLA/Compactin0.790 0.880 0.810 0.500 0.290 0.330 0.580
Rpa1
KLA  Compactin  Compactin+KLA
 NM_026653 replication protein A1 (Rpa1), mRNA [NM_026653] KLA0.900 0.830 0.770 0.560 0.340 0.450 0.480
Compactin0.840 0.970 0.900 0.870 0.940 1.090 0.860
KLA/Compactin0.920 0.920 0.870 0.580 0.310 0.360 0.500
Rpa2
KLA  Compactin  Compactin+KLA
 D00812 mRNA for 30-kDa subunit of replication protein A, complete cds. [D00812] KLA0.790 0.880 0.560 0.400 0.510 0.310 0.390
Compactin0.960 0.950 0.850 0.820 0.910 1.180 0.670
KLA/Compactin0.800 0.800 0.650 0.410 0.300 0.230 0.390
Rpa2
KLA  Compactin  Compactin+KLA
 NM_011284 replication protein A2 (Rpa2), mRNA [NM_011284] KLA0.940 0.870 0.720 0.430 0.450 0.390 0.410
Compactin0.900 0.990 0.880 1.060 0.950 1.040 0.760
KLA/Compactin0.910 0.970 0.690 0.460 0.390 0.310 0.370
Rpa3
KLA  Compactin  Compactin+KLA
 146141223 replication protein A3 KLA0.900 0.900 0.700 0.910 0.450 0.440 0.570
Compactin1.020 0.990 0.950 0.930 0.980 1.000 0.760
KLA/Compactin0.770 0.850 0.750 0.680 0.560 0.450 0.460
Rpa3
KLA  Compactin  Compactin+KLA
 NM_026632 replication protein A3 (Rpa3), mRNA [NM_026632] KLA0.950 0.990 0.810 1.030 0.550 0.490 0.580
Compactin1.090 1.090 0.980 1.210 1.040 0.960 0.850
KLA/Compactin1.020 0.990 0.830 0.870 0.550 0.520 0.490
Shfm1
KLA  Compactin  Compactin+KLA
 NM_009169 split hand/foot malformation (ectrodactyly) type 1 (Shfm1), mRNA [NM_009169] KLA0.950 0.890 0.920 1.000 1.010 1.280 1.400
Compactin0.940 0.930 1.080 0.980 1.190 0.990 1.090
KLA/Compactin0.970 0.900 0.880 1.010 1.200 1.370 1.520
Ssbp1
KLA  Compactin  Compactin+KLA
 NM_028358 single-stranded DNA binding protein 1 (Ssbp1), transcript variant 2, mRNA [NM_028358] KLA0.880 0.830 0.840 0.960 0.720 0.700 0.630
Compactin0.870 0.910 0.830 0.830 0.880 0.890 1.030
KLA/Compactin0.770 0.830 0.860 0.900 0.790 0.610 0.480
Ssbp1
KLA  Compactin  Compactin+KLA
 NM_028358 single-stranded DNA binding protein 1 (Ssbp1), transcript variant 2, mRNA [NM_028358] KLA0.990 0.940 0.990 1.020 0.740 0.650 0.570
Compactin1.080 1.030 1.040 1.120 1.040 1.100 0.920
KLA/Compactin0.940 0.990 0.930 1.020 0.770 0.770 0.470
Ssbp1
KLA  Compactin  Compactin+KLA
 NM_212468 single-stranded DNA binding protein 1 (Ssbp1), transcript variant 1, mRNA [NM_212468] KLA0.930 0.980 0.980 1.000 0.890 0.840 0.860
Compactin1.000 1.010 1.010 1.090 1.050 0.970 1.010
KLA/Compactin0.940 0.920 1.000 0.960 0.920 0.770 0.790
Ssbp1
KLA  Compactin  Compactin+KLA
 NM_212468 single-stranded DNA binding protein 1 (Ssbp1), transcript variant 1, mRNA [NM_212468] KLA1.000 0.970 1.000 0.930 0.960 0.870 0.840
Compactin0.980 0.990 0.970 0.960 0.970 0.970 0.930
KLA/Compactin0.900 0.920 0.990 0.930 0.960 0.730 0.780
Top3a
KLA  Compactin  Compactin+KLA
 NM_009410 topoisomerase (DNA) III alpha (Top3a), mRNA [NM_009410] KLA1.080 0.870 0.890 1.230 0.960 1.010 0.930
Compactin1.040 1.080 1.000 0.920 0.930 1.010 0.870
KLA/Compactin1.020 0.990 0.870 1.080 1.090 0.870 0.870
Top3a
KLA  Compactin  Compactin+KLA
 NM_009410 topoisomerase (DNA) III alpha (Top3a), mRNA [NM_009410] KLA1.080 0.950 0.830 1.090 1.050 0.970 0.950
Compactin1.020 1.060 0.870 0.870 0.940 1.160 0.820
KLA/Compactin0.840 0.910 0.850 1.390 0.960 0.980 1.020
Top3b
KLA  Compactin  Compactin+KLA
 NM_011624 topoisomerase (DNA) III beta (Top3b), mRNA [NM_011624] KLA0.990 0.970 1.040 0.860 0.830 1.170 0.860
Compactin1.010 1.030 0.990 1.100 0.990 1.000 1.080
KLA/Compactin1.040 1.070 0.950 0.830 1.130 1.100 0.670
Xrcc2
KLA  Compactin  Compactin+KLA
 AK085093 13 days embryo lung cDNA, RIKEN full-length enriched library, clone:D430035K04 product:hypothetical protein, full insert sequence. [AK085093] KLA0.950 1.070 1.070 1.020 0.960 1.030 0.960
Compactin1.090 0.990 1.020 1.040 0.960 1.070 1.070
KLA/Compactin1.000 1.040 1.060 1.010 0.870 0.880 0.950
Xrcc2
KLA  Compactin  Compactin+KLA
 NM_020570 X-ray repair complementing defective repair in Chinese hamster cells 2 (Xrcc2), mRNA [NM_020570] KLA1.000 1.040 0.980 0.800 0.720 0.660 0.830
Compactin1.060 1.120 1.070 1.010 1.020 1.000 0.890
KLA/Compactin1.010 1.080 1.010 0.740 0.730 0.680 0.780
Xrcc2
KLA  Compactin  Compactin+KLA
 NM_020570 X-ray repair complementing defective repair in Chinese hamster cells 2 (Xrcc2), mRNA [NM_020570] KLA1.070 1.210 1.180 0.980 0.810 0.890 0.860
Compactin1.080 1.100 1.050 1.080 0.900 1.070 1.030
KLA/Compactin1.140 1.150 1.240 0.940 0.850 0.780 0.840
Xrcc3
KLA  Compactin  Compactin+KLA
 NM_028875 X-ray repair complementing defective repair in Chinese hamster cells 3 (Xrcc3), mRNA [NM_028875] KLA1.190 0.990 0.750 0.680 0.560 0.550 0.630
Compactin0.990 0.930 0.960 1.040 0.870 0.940 0.800
KLA/Compactin0.980 1.030 0.790 0.660 0.540 0.460 0.640