Microarray analysis of RAW 264.7 cells treated with Kdo2-lipid A (KLA) and compactin (full time course)

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Kdo2-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: RNA polymerase (mmu03020)

Legend:graph_icon: View data/graphs for replicates
Gene symbol    Time course plot Accession Description Treatment 30min 1hr 2hr 4hr 8hr 12hr 24hr
Polr1e
KLA  Compactin  Compactin+KLA
 NM_022811 polymerase (RNA) I polypeptide E (Polr1e), mRNA [NM_022811] KLA0.980 1.020 1.120 0.990 0.740 0.910 0.720
Compactin0.980 0.910 0.980 1.040 0.910 0.970 0.870
KLA/Compactin1.010 1.030 1.000 1.000 0.810 0.780 0.620
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.000 1.050 0.970 0.970 1.120 1.000 1.000
Compactin0.890 0.910 0.970 0.900 0.960 1.140 0.910
KLA/Compactin0.860 1.000 1.060 1.010 0.930 1.010 1.010
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.040 0.980 1.100 1.000 1.120 1.020 0.870
Compactin0.910 1.000 1.090 0.920 1.040 1.030 0.940
KLA/Compactin1.050 1.040 1.170 1.100 0.980 1.000 1.040
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.060 1.120 1.080 1.130 1.010 0.960 0.920
Compactin0.930 0.990 0.970 0.980 1.140 1.090 0.860
KLA/Compactin1.090 1.160 1.050 1.020 0.940 0.890 0.950
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.070 1.130 1.290 1.150 1.030 0.990 0.900
Compactin0.970 1.020 1.140 1.020 1.080 1.060 1.010
KLA/Compactin1.140 1.140 1.190 1.170 1.120 0.980 0.920
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.080 1.040 1.110 1.030 0.950 1.000 0.970
Compactin0.930 0.970 1.000 1.070 1.060 0.940 0.850
KLA/Compactin1.010 1.150 1.130 1.130 1.040 0.990 0.990
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.120 1.130 1.080 1.100 1.010 1.010 0.930
Compactin0.970 0.980 1.010 1.020 1.090 1.030 0.910
KLA/Compactin1.050 1.120 1.080 1.060 1.070 1.040 0.940
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.150 1.070 1.240 1.150 1.000 1.040 1.030
Compactin1.100 1.000 1.070 1.140 1.050 1.050 0.910
KLA/Compactin1.200 1.140 1.170 1.220 0.990 0.990 0.980
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.160 1.020 1.220 1.040 1.020 1.010 0.960
Compactin0.990 0.970 1.090 0.940 0.950 1.040 0.840
KLA/Compactin1.140 1.060 1.210 1.120 1.000 1.000 0.990
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.170 1.040 1.100 1.090 1.000 0.980 0.980
Compactin0.940 0.960 1.000 0.930 1.050 1.060 0.880
KLA/Compactin1.040 1.050 1.100 1.060 1.020 0.940 0.980
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.230 1.110 1.220 1.170 1.030 1.120 1.010
Compactin1.070 1.010 1.040 1.100 1.150 1.020 0.880
KLA/Compactin1.180 1.190 1.160 1.260 1.090 1.030 1.070
Polr2a
KLA  Compactin  Compactin+KLA
 NM_009089 polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA [NM_009089] KLA1.320 1.130 1.180 1.150 1.020 1.060 0.940
Compactin1.090 0.950 1.140 1.140 1.070 1.040 0.940
KLA/Compactin1.260 1.150 1.190 1.240 1.070 0.970 1.000
Polr2b
KLA  Compactin  Compactin+KLA
 NM_153798 polymerase (RNA) II (DNA directed) polypeptide B (Polr2b), mRNA [NM_153798] KLA0.850 1.030 0.690 0.810 0.940 0.560 0.540
Compactin0.880 0.910 0.960 0.860 0.960 1.020 0.820
KLA/Compactin0.920 1.020 0.800 0.760 0.700 0.550 0.730
Polr2b
KLA  Compactin  Compactin+KLA
 NM_153798 polymerase (RNA) II (DNA directed) polypeptide B (Polr2b), mRNA [NM_153798] KLA0.900 0.950 0.960 0.750 0.720 0.720 0.610
Compactin0.870 0.910 0.890 0.900 0.850 0.870 0.880
KLA/Compactin0.900 0.920 0.990 0.730 0.690 0.590 0.560
Polr2c
KLA  Compactin  Compactin+KLA
 NM_009090 polymerase (RNA) II (DNA directed) polypeptide C (Polr2c), mRNA [NM_009090] KLA1.220 1.070 1.230 1.390 1.180 1.340 2.120
Compactin1.250 1.210 1.100 1.300 1.030 1.030 1.260
KLA/Compactin1.150 1.080 1.270 1.560 1.410 1.300 1.970
Polr2d
KLA  Compactin  Compactin+KLA
 NM_027101 polymerase (RNA) II (DNA directed) polypeptide D (Polr2d), transcript variant 2, mRNA [NM_027101] KLA0.970 0.980 0.890 0.990 0.870 0.800 1.150
Compactin0.980 1.020 1.060 1.040 1.070 1.020 1.070
KLA/Compactin0.990 0.940 1.010 0.830 0.880 0.840 1.020
Polr2e
KLA  Compactin  Compactin+KLA
 AK010567 ES cells cDNA, RIKEN full-length enriched library, clone:2410021N14 product:polymerase (RNA) II (DNA directed) polypeptide E, full insert sequence. [AK010567] KLA0.930 0.920 0.720 0.830 0.890 0.590 0.690
Compactin0.890 0.960 0.950 0.850 1.110 1.160 1.070
KLA/Compactin0.960 0.940 0.790 0.740 0.590 0.560 0.930
Polr2e
KLA  Compactin  Compactin+KLA
 NM_025554 polymerase (RNA) II (DNA directed) polypeptide E (Polr2e), mRNA [NM_025554] KLA0.910 0.970 0.950 0.840 0.790 0.750 0.730
Compactin0.920 0.930 0.840 0.920 0.940 1.110 1.130
KLA/Compactin0.860 0.900 0.920 0.900 0.750 0.650 0.670
Polr2e
KLA  Compactin  Compactin+KLA
 NM_025554 polymerase (RNA) II (DNA directed) polypeptide E (Polr2e), mRNA [NM_025554] KLA1.280 0.990 1.080 1.020 0.800 0.770 1.070
Compactin1.300 1.190 1.020 1.300 1.240 1.180 1.060
KLA/Compactin1.200 0.960 1.010 1.020 1.010 0.740 0.750
Polr2f
KLA  Compactin  Compactin+KLA
 NM_027231 polymerase (RNA) II (DNA directed) polypeptide F (Polr2f), mRNA [NM_027231] KLA1.050 1.110 1.060 1.040 0.700 0.740 0.750
Compactin1.090 1.050 1.110 1.270 1.050 0.990 0.940
KLA/Compactin0.920 1.000 1.010 0.980 0.750 0.800 0.720
Polr2f
KLA  Compactin  Compactin+KLA
 NM_027231 polymerase (RNA) II (DNA directed) polypeptide F (Polr2f), mRNA [NM_027231] KLA1.120 1.140 1.000 1.060 0.860 0.790 0.770
Compactin1.050 1.090 1.130 1.160 1.080 0.980 0.950
KLA/Compactin1.020 0.910 1.110 1.140 0.760 0.590 0.770
Polr2g
KLA  Compactin  Compactin+KLA
 NM_026329 polymerase (RNA) II (DNA directed) polypeptide G (Polr2g), mRNA [NM_026329] KLA0.910 0.960 1.110 1.390 0.960 0.880 1.390
Compactin0.910 0.870 0.910 1.040 0.900 0.890 1.110
KLA/Compactin0.960 0.960 0.880 1.290 1.320 1.000 1.130
Polr2h
KLA  Compactin  Compactin+KLA
 NM_145632 polymerase (RNA) II (DNA directed) polypeptide H (Polr2h), mRNA [NM_145632] KLA0.980 1.040 1.200 1.130 0.840 0.820 1.060
Compactin1.040 0.970 1.040 1.080 1.050 1.000 0.980
KLA/Compactin1.080 1.030 1.050 1.130 0.900 0.810 0.830
Polr2i
KLA  Compactin  Compactin+KLA
 NM_027259 polymerase (RNA) II (DNA directed) polypeptide I (Polr2i), mRNA [NM_027259] KLA0.860 0.910 0.780 0.730 0.830 0.960 1.340
Compactin0.890 0.980 0.900 0.900 0.930 0.940 1.080
KLA/Compactin0.830 0.860 0.810 0.770 0.720 0.920 1.280
Polr2j
KLA  Compactin  Compactin+KLA
 NM_011293 polymerase (RNA) II (DNA directed) polypeptide J (Polr2j), mRNA [NM_011293] KLA0.880 0.970 0.930 0.960 0.770 0.690 0.900
Compactin0.940 0.900 0.920 0.780 1.070 1.150 0.920
KLA/Compactin0.900 0.990 0.900 0.770 0.620 0.590 1.040
Polr2l
KLA  Compactin  Compactin+KLA
 XM_888022 gb|PREDICTED: Mus musculus polymerase (RNA) II (DNA directed) polypeptide L (Polr2l), mRNA [XM_888022] KLA1.100 1.160 0.970 1.080 0.620 0.680 0.630
Compactin0.980 1.040 0.970 1.040 1.030 1.130 1.070
KLA/Compactin0.970 1.000 0.960 0.970 0.760 0.610 0.630
Polr3a
KLA  Compactin  Compactin+KLA
 AK039440 adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330043C08 product:hypothetical protein, full insert sequence. [AK039440] KLA0.810 1.100 0.930 0.790 0.930 1.050 0.810
Compactin1.020 1.010 0.960 0.750 1.100 0.950 1.100
KLA/Compactin0.780 1.000 1.050 0.850 0.780 0.800 0.860
Polr3a
KLA  Compactin  Compactin+KLA
 NM_001081247 polymerase (RNA) III (DNA directed) polypeptide A (Polr3a), mRNA [NM_001081247] KLA1.170 1.030 1.260 1.210 1.230 1.360 1.200
Compactin1.190 1.060 1.140 1.190 0.980 1.130 1.080
KLA/Compactin1.340 1.190 1.200 1.350 1.160 1.220 0.980
Polr3b
KLA  Compactin  Compactin+KLA
 NM_027423 polymerase (RNA) III (DNA directed) polypeptide B (Polr3b), mRNA [NM_027423] KLA0.910 1.000 0.790 0.810 1.040 0.550 0.460
Compactin0.880 0.920 0.820 0.800 1.090 1.050 0.910
KLA/Compactin0.870 1.010 0.920 0.920 0.610 0.520 0.400
Polr3b
KLA  Compactin  Compactin+KLA
 NM_027423 polymerase (RNA) III (DNA directed) polypeptide B (Polr3b), mRNA [NM_027423] KLA0.960 1.020 0.940 1.000 0.970 0.910 0.930
Compactin0.970 0.950 1.010 1.060 1.050 0.940 0.990
KLA/Compactin1.010 0.980 1.010 1.010 0.950 1.050 0.930
Polr3c
KLA  Compactin  Compactin+KLA
 XM_131049 gb|PREDICTED: Mus musculus polymerase (RNA) III (DNA directed) polypeptide C, transcript variant 1 (Polr3c), mRNA [XM_131049] KLA0.920 0.940 0.940 1.250 1.280 1.060 1.270
Compactin0.890 0.910 0.950 0.870 0.930 1.090 1.040
KLA/Compactin0.860 1.010 1.100 1.070 1.200 1.280 1.560
Polr3c
KLA  Compactin  Compactin+KLA
 XM_131049 gb|PREDICTED: Mus musculus polymerase (RNA) III (DNA directed) polypeptide C, transcript variant 1 (Polr3c), mRNA [XM_131049] KLA1.220 1.110 1.140 1.240 1.350 1.370 1.530
Compactin1.200 1.280 1.130 1.390 1.160 1.110 1.010
KLA/Compactin1.250 1.070 1.270 1.360 1.450 1.730 1.440
Polr3d
KLA  Compactin  Compactin+KLA
 NM_025945 polymerase (RNA) III (DNA directed) polypeptide D (Polr3d), mRNA [NM_025945] KLA1.310 1.620 1.680 1.770 1.270 1.340 1.070
Compactin1.310 1.180 1.100 1.210 1.010 1.100 1.360
KLA/Compactin1.310 1.690 1.740 1.800 1.320 1.050 0.810
Polr3e
KLA  Compactin  Compactin+KLA
 AK162059 adult male adrenal gland cDNA, RIKEN full-length enriched library, clone:7330401M11 product:sex-lethal interactor homolog (Drosophila), full insert sequence [AK162059] KLA0.930 0.810 0.850 0.860 0.680 0.630 0.540
Compactin1.180 1.110 1.100 1.180 1.070 0.870 0.940
KLA/Compactin1.040 0.760 0.860 0.830 0.660 0.490 0.460
Polr3e
KLA  Compactin  Compactin+KLA
 NM_025298 polymerase (RNA) III (DNA directed) polypeptide E (Polr3e), mRNA [NM_025298] KLA1.330 1.070 0.980 0.940 0.760 0.810 0.690
Compactin0.960 1.140 1.190 1.020 0.930 0.910 0.830
KLA/Compactin1.150 0.980 1.080 0.960 0.800 0.650 0.580
Polr3f
KLA  Compactin  Compactin+KLA
 NM_029763 polymerase (RNA) III (DNA directed) polypeptide F (Polr3f), mRNA [NM_029763] KLA0.960 1.080 1.210 1.200 1.060 1.110 1.000
Compactin0.950 1.020 0.980 1.020 0.830 0.970 0.990
KLA/Compactin1.070 1.040 1.030 1.160 1.010 1.020 0.930
Polr3f
KLA  Compactin  Compactin+KLA
 NM_029763 polymerase (RNA) III (DNA directed) polypeptide F (Polr3f), mRNA [NM_029763] KLA1.090 1.150 1.210 1.170 1.050 0.870 0.640
Compactin1.080 1.050 1.080 1.130 1.010 1.030 1.040
KLA/Compactin1.060 1.050 1.200 1.150 0.950 0.710 0.620
Polr3g
KLA  Compactin  Compactin+KLA
 NM_001081176 polymerase (RNA) III (DNA directed) polypeptide G (Polr3g), mRNA [NM_001081176] KLA0.930 0.620 0.780 0.620 0.570 0.640 0.840
Compactin1.090 1.020 0.870 0.780 1.100 1.080 0.920
KLA/Compactin0.900 0.850 0.810 0.610 0.520 0.690 0.710
Polr3g
KLA  Compactin  Compactin+KLA
 NM_001081176 polymerase (RNA) III (DNA directed) polypeptide G (Polr3g), mRNA [NM_001081176] KLA1.050 0.990 1.270 1.020 0.900 0.950 0.890
Compactin1.200 1.180 1.170 1.160 1.020 0.950 0.930
KLA/Compactin1.160 0.950 1.170 1.060 0.980 0.850 0.880
Polr3g
KLA  Compactin  Compactin+KLA
 NM_001081176 polymerase (RNA) III (DNA directed) polypeptide G (Polr3g), mRNA [NM_001081176] KLA1.100 0.950 1.200 1.010 0.930 1.050 0.920
Compactin1.040 1.060 1.010 0.990 1.000 1.040 0.990
KLA/Compactin1.070 1.020 1.130 1.010 0.960 0.930 0.850
Polr3gl
KLA  Compactin  Compactin+KLA
 NM_027241 polymerase (RNA) III (DNA directed) polypeptide G like (Polr3gl), mRNA [NM_027241] KLA0.880 0.920 0.760 0.640 0.660 0.850 0.770
Compactin0.900 0.970 0.880 0.920 1.070 1.150 1.190
KLA/Compactin0.870 0.900 0.660 0.670 0.850 0.800 0.800
Polr3h
KLA  Compactin  Compactin+KLA
 146149315 polymerase (RNA) III (DNA directed) polypeptide H KLA0.950 1.020 0.990 0.950 0.950 0.840 0.920
Compactin1.030 1.020 1.050 1.010 0.950 1.020 0.960
KLA/Compactin1.030 0.970 0.910 0.850 0.920 0.890 0.870
Polr3h
KLA  Compactin  Compactin+KLA
 NM_030229 polymerase (RNA) III (DNA directed) polypeptide H (Polr3h), mRNA [NM_030229] KLA1.000 0.980 0.940 0.900 0.890 0.940 0.830
Compactin1.140 1.030 1.050 1.070 1.000 0.950 0.850
KLA/Compactin0.980 0.980 0.830 1.000 0.900 0.780 0.860
Polr3k
KLA  Compactin  Compactin+KLA
 NM_025901 polymerase (RNA) III (DNA directed) polypeptide K (Polr3k), mRNA [NM_025901] KLA0.940 0.960 0.880 0.790 0.550 0.610 0.860
Compactin1.080 1.100 1.150 1.180 1.000 0.970 0.890
KLA/Compactin1.000 0.880 0.900 0.780 0.600 0.600 0.740
Polr3k
KLA  Compactin  Compactin+KLA
 NM_025901 polymerase (RNA) III (DNA directed) polypeptide K (Polr3k), mRNA [NM_025901] KLA1.070 0.900 0.860 0.680 0.530 0.580 0.460
Compactin0.970 1.100 1.120 1.110 0.930 0.970 0.830
KLA/Compactin1.030 0.850 0.820 0.730 0.500 0.420 0.370
Polr3k
KLA  Compactin  Compactin+KLA
 NM_025901 polymerase (RNA) III (DNA directed) polypeptide K (Polr3k), mRNA [NM_025901] KLA1.190 1.060 1.020 0.960 0.700 0.720 1.020
Compactin1.130 1.190 1.070 1.290 1.040 0.890 0.890
KLA/Compactin1.070 1.060 0.920 1.020 0.790 0.580 0.790
Rpo1-1
KLA  Compactin  Compactin+KLA
 119226250 RNA polymerase 1-1 KLA0.860 1.100 1.270 1.020 1.020 0.970 0.880
Compactin0.870 0.980 0.940 1.130 0.950 0.920 0.970
KLA/Compactin0.950 1.140 1.230 1.000 0.990 0.980 0.780
Rpo1-1
KLA  Compactin  Compactin+KLA
 NM_009085 RNA polymerase 1-1 (Rpo1-1), mRNA [NM_009085] KLA1.020 1.070 1.090 0.980 0.900 0.780 0.810
Compactin0.990 0.960 0.930 0.910 1.020 0.860 0.810
KLA/Compactin0.860 1.120 1.060 0.950 1.100 1.080 0.950
Rpo1-2
KLA  Compactin  Compactin+KLA
 AK052672 0 day neonate kidney cDNA, RIKEN full-length enriched library, clone:D630020H17 product:RNA polymerase 1-2 (128 kDa subunit), full insert sequence. [AK052672] KLA0.990 1.060 1.040 1.020 1.020 1.040 1.050
Compactin0.980 1.010 0.950 0.960 0.990 0.980 1.080
KLA/Compactin0.990 1.030 1.060 0.950 1.030 0.990 1.120
Rpo1-2
KLA  Compactin  Compactin+KLA
 NM_009086 RNA polymerase 1-2 (Rpo1-2), mRNA [NM_009086] KLA1.130 1.080 1.400 1.000 0.830 0.710 0.460
Compactin1.180 1.040 1.060 1.130 0.930 0.970 0.930
KLA/Compactin1.190 1.140 1.370 1.080 0.710 0.510 0.380
Rpo1-3
KLA  Compactin  Compactin+KLA
 NM_009087 RNA polymerase 1-3 (Rpo1-3), transcript variant 1, mRNA [NM_009087] KLA0.880 0.980 1.020 1.150 1.160 1.030 1.210
Compactin0.820 0.980 0.940 0.880 0.860 0.950 0.950
KLA/Compactin0.840 0.960 1.010 1.160 0.820 0.940 1.210
Rpo1-3
KLA  Compactin  Compactin+KLA
 NM_181730 RNA polymerase 1-3 (Rpo1-3), transcript variant 2, mRNA [NM_181730] KLA1.060 1.190 1.090 1.320 1.120 0.940 1.140
Compactin1.050 1.080 1.070 1.200 1.100 0.900 0.990
KLA/Compactin1.080 1.040 1.150 1.360 1.190 1.040 1.030
Rpo1-4
KLA  Compactin  Compactin+KLA
 34328145 RNA polymerase 1-4 KLA1.170 1.130 1.100 0.890 0.820 0.850 1.100
Compactin1.080 1.110 1.040 1.210 0.990 1.000 1.170
KLA/Compactin1.190 1.180 1.100 0.970 0.750 0.930 0.780
Rpo1-4
KLA  Compactin  Compactin+KLA
 NM_009088 RNA polymerase 1-4 (Rpo1-4), mRNA [NM_009088] KLA0.810 0.890 0.810 0.730 0.970 0.710 0.840
Compactin0.850 0.710 0.780 0.750 0.950 1.160 1.100
KLA/Compactin0.690 1.000 0.910 0.780 0.570 0.630 0.800
Twistnb
KLA  Compactin  Compactin+KLA
 NM_172253 TWIST neighbor (Twistnb), mRNA [NM_172253] KLA0.830 1.110 1.220 0.940 0.720 0.760 0.700
Compactin0.800 0.940 0.880 1.020 0.900 0.920 1.040
KLA/Compactin0.860 1.160 1.170 0.890 0.760 0.680 0.520
Twistnb
KLA  Compactin  Compactin+KLA
 NM_172253 TWIST neighbor (Twistnb), mRNA [NM_172253] KLA1.000 1.290 1.290 1.160 1.010 0.900 0.820
Compactin0.990 0.990 0.900 0.930 1.480 0.900 1.050
KLA/Compactin1.000 1.320 1.310 1.010 0.980 0.880 0.690
Znrd1
KLA  Compactin  Compactin+KLA
 NM_023162 zinc ribbon domain containing, 1 (Znrd1), mRNA [NM_023162] KLA1.050 1.230 1.080 1.380 1.520 1.430 1.540
Compactin0.870 1.090 0.970 1.020 0.930 1.100 1.040
KLA/Compactin0.840 1.150 1.320 1.310 1.260 1.340 1.700
Znrd1
KLA  Compactin  Compactin+KLA
 NM_023162 zinc ribbon domain containing, 1 (Znrd1), mRNA [NM_023162] KLA1.150 1.270 1.460 1.540 1.360 1.430 1.770
Compactin1.220 1.070 1.150 1.230 1.000 0.980 1.130
KLA/Compactin1.160 1.280 1.320 1.640 1.570 1.440 1.680