Microarray analysis of RAW 264.7 cells treated with Kdo₂-lipid A (KLA) and compactin (full time course)

Kdo₂-Lipid A / compactin gene array data - treatment:control ratios

KEGG pathway: Vitamin B6 metabolism (mmu00750)

Legend: : View data/graphs for replicates

Gene symbol	Time course plot	Accession	Description	Treatment	30min	1hr	2hr	4hr	8hr	12hr	24hr
Aox1	KLA  Compactin  Compactin+KLA	NM_009676	aldehyde oxidase 1 (Aox1), mRNA [NM_009676]	KLA	0.970	1.000	1.030	1.060	1.040	1.050	1.060
				Compactin	0.960	1.050	0.990	1.090	1.100	0.960	0.990
				KLA/Compactin	0.980	1.000	0.970	0.920	1.040	1.040	0.980
Aox3	KLA  Compactin  Compactin+KLA	NM_023617	aldehyde oxidase 3 (Aox3), mRNA [NM_023617]	KLA	1.010	0.970	0.990	1.000	0.920	0.970	1.030
				Compactin	0.960	0.960	1.020	0.960	0.950	1.010	1.050
				KLA/Compactin	1.020	1.010	1.070	1.020	1.020	0.970	1.010
Aox4	KLA  Compactin  Compactin+KLA	NM_023631	aldehyde oxidase 4 (Aox4), mRNA [NM_023631]	KLA	0.950	1.030	1.020	1.000	0.970	0.910	1.080
				Compactin	1.090	1.070	1.020	1.030	1.020	1.040	0.990
				KLA/Compactin	0.990	1.080	1.070	0.960	1.000	1.010	1.000
Pdxk	KLA  Compactin  Compactin+KLA	NM_172134	pyridoxal (pyridoxine, vitamin B6) kinase (Pdxk), mRNA [NM_172134]	KLA	0.910	1.020	1.040	0.960	0.760	1.000	1.980
				Compactin	0.950	1.010	0.930	1.090	0.840	0.860	0.700
				KLA/Compactin	0.890	1.040	0.960	0.890	0.700	0.840	1.700
Pdxk	KLA  Compactin  Compactin+KLA	NM_172134	pyridoxal (pyridoxine, vitamin B6) kinase (Pdxk), mRNA [NM_172134]	KLA	0.930	0.760	0.540	0.290	0.450	0.430	0.660
				Compactin	0.840	0.920	0.880	0.790	0.890	0.660	0.470
				KLA/Compactin	0.840	0.860	0.470	0.220	0.330	0.410	0.840
Pdxk	KLA  Compactin  Compactin+KLA	NM_172134	pyridoxal (pyridoxine, vitamin B6) kinase (Pdxk), mRNA [NM_172134]	KLA	1.150	1.090	1.180	1.190	0.910	1.040	1.900
				Compactin	1.180	1.160	1.190	1.150	0.870	0.850	0.690
				KLA/Compactin	1.030	0.940	1.060	0.990	0.720	0.810	1.600
Pdxk	KLA  Compactin  Compactin+KLA	NM_172134	pyridoxal (pyridoxine, vitamin B6) kinase (Pdxk), mRNA [NM_172134]	KLA	1.310	1.110	0.680	0.380	0.630	0.580	0.940
				Compactin	1.290	1.300	1.270	1.230	0.950	0.760	0.610
				KLA/Compactin	1.350	0.990	0.680	0.360	0.440	0.400	0.750
Pdxp	KLA  Compactin  Compactin+KLA	85838507	pyridoxal (pyridoxine, vitamin B6) phosphatase	KLA	1.030	0.940	0.350	0.280	0.370	0.280	0.430
				Compactin	0.960	1.150	1.140	0.870	1.160	1.120	0.900
				KLA/Compactin	0.960	1.200	0.410	0.240	0.280	0.250	0.550
Pdxp	KLA  Compactin  Compactin+KLA	NM_020271	pyridoxal (pyridoxine, vitamin B6) phosphatase (Pdxp), mRNA [NM_020271]	KLA	0.890	0.980	0.480	0.340	0.390	0.400	0.640
				Compactin	0.940	0.960	1.080	0.930	1.190	1.280	0.970
				KLA/Compactin	0.970	1.100	0.490	0.400	0.360	0.360	0.630
Phospho2	KLA  Compactin  Compactin+KLA	AK010147	adult male tongue cDNA, RIKEN full-length enriched library, clone:2310074E15 product:unclassifiable, full insert sequence. [AK010147]	KLA	0.980	0.990	0.990	0.940	1.010	1.000	0.930
				Compactin	0.980	0.960	1.030	0.960	0.910	1.000	1.070
				KLA/Compactin	1.030	0.930	0.980	0.970	1.010	0.950	1.030
Phospho2	KLA  Compactin  Compactin+KLA	NM_028521	phosphatase, orphan 2 (Phospho2), mRNA [NM_028521]	KLA	0.940	0.810	1.030	1.210	1.210	1.180	1.270
				Compactin	1.040	1.070	1.030	1.170	1.000	0.940	1.040
				KLA/Compactin	1.060	0.920	0.920	1.270	1.170	1.200	1.200
Pnpo	KLA  Compactin  Compactin+KLA	NM_134021	pyridoxine 5-phosphate oxidase (Pnpo), mRNA [NM_134021]	KLA	1.140	1.090	0.910	0.820	0.790	0.940	1.080
				Compactin	1.050	1.190	1.220	1.100	1.150	0.880	0.930
				KLA/Compactin	1.040	0.980	0.970	0.870	0.700	0.740	0.750
Psat1	KLA  Compactin  Compactin+KLA	NM_177420	phosphoserine aminotransferase 1 (Psat1), mRNA [NM_177420]	KLA	1.330	0.980	1.010	0.860	1.310	1.430	0.940
				Compactin	1.090	1.090	1.140	1.160	1.210	1.230	1.290
				KLA/Compactin	1.160	1.060	0.980	1.100	1.270	1.170	1.120