Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: CE(18:2) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 105.31 4.04 6.91 3.47 2.33 5.35 3.46 5.02 2.86 3.91 1.95 1.89 2.88 4.71 2.42 1 2.86 2.02 5.2 3.7 3.2 1.93 1.6 2.59 2.81 1.2 1.28 1.18 0.96 7.91 7.53 6.05 6.87 9.36 6.69 6.7 9.48 7.24 7.92 6.1 7.11 6.44 3.73 3.76 4.41 - 3.12 3.06 4.25 1.93 3.07 3.01 1.21 0.989 1.09 0.523 0.555 0.095 0.651 0.542 0.497 0.488 0.571 0.568 0.528 0.659 0.29 0.252 0.244 0.086 0.4 0.265 2.28 0.616 0.27 0.238 0.597 0.074 0.403 0.232 2.5 0.656 0.311 0.246 0.538 1.2 1.46 0.551 0.934 0.077 0.507 0.458 0.418 0.409 0.693 0.454 0.644 0.772 0.352 0.255 0.195 0.67 0.02 0.06 5.48 4.48 5.37 6.13 6.05 7.29 5.98 15.7 5.42 5.57 19.8 16.8 16.4 11.8 24.9 12.5 7.5 9.7 7.97 6.87 9.53 9.45 8.35 10.6 30 371 67.5 92 145 192 159 146 162 291 119 272 315 180 304 217 143 316 339 260 809 225 624 391 715 315 305 640 596 762 276 462 477 347 1118 462 771 598 665 441 1638 1164 1177 357 370 687 488 1424 386 516 527 592 435 290 259 365 76.6 565 2403 1047 281 73 513 206 177 1509 100 188 95.3 1120 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070914) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070914) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080212) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080219) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080226) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD080211) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD080311) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD080408) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090512) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090716) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090805) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090805) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMST01020008 CE(18:2) - 0.15 - 0.43 0.16 0.2 0.73 1.17 0.17 0.14 0.52 0.59 0.26 0.14 0.34 0.43 0.5 0.19 0.66 0.28 0.39 0.12 0.59 0.42 0.41 0.16 0.52 0.41 0.39 - 0.4 0.41 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LMST01020008 CE(18:2) - 0.19 - 0.69 0.16 0.26 0.78 1.1 0.14 0.86 1.03 0.9 0.23 0.18 0.78 0.65 2.33 0.18 3.11 1.02 0.41 - 0.99 0.71 0.94 - 0.67 3.87 0.68 - 0.8 0.73 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LMST01020008 CE(18:2) - 0.32 - 1.5 0.5 0.45 1.82 1.38 0.37 0.45 2.09 1.52 0.5 0.34 1.41 0.69 0.78 0.27 1.75 2.03 0.89 0.31 1.87 2.35 1.38 0.37 2.08 1.22 2.69 0.29 4.36 1.26 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMST01020008 CE(18:2) - 1.47 - 4.44 1.76 2.11 8.24 7.79 2.03 1.7 5.59 6.58 2.02 1.22 4.96 5.27 3.6 1.59 5.14 2.58 4.27 1.31 8.02 6.35 4 1.3 7.21 6.22 4.6 - 4.06 4.64 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LMST01020008 CE(18:2) - 1.43 - 6.53 1.28 2.29 6.94 12 1.34 8.51 10.2 10.4 1.75 2.05 9.55 7.04 18 1.17 29.1 7.19 4.16 - 11.8 7.41 7.93 - 7.19 53.6 6.78 - 8.55 7.38 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LMST01020008 CE(18:2) - 2.59 - 11.2 3.61 2.62 10.8 9.82 2.7 2.79 13.6 11.1 3.51 2.24 8.06 5.43 5.36 1.84 7.85 9.58 6.01 2.09 14.1 13.1 7.11 1.69 11.2 8.65 14.4 1.39 20.2 6.51 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090512) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090716) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE060920) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070616) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070623) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070702) LMST01020008 CE(18:2) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070802) LMST01020008 CE(18:2) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070712) LMST01020008 CE(18:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070712) LMST01020008 CE(18:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070712) LMST01020008 CE(18:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070917) LMST01020008 CE(18:2) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) CE(18:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) LMST01020008 CE(18:2) pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) CE(18:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) CE(18:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) CE(18:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) LMST01020008 CE(18:2) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0002) LMST01020008 CE(18:2) nmol/ml Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0011) LMST01020008 CE(18:2) pmol/mg