Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Small cell lung cancer (mmu05222)

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Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
AK044510
KLA  ATP  ATP+KLA
 AK044510 adult retina cDNA, RIKEN full-length enriched library, clone:A930017M14 product:laminin, alpha 1, full insert sequence. [AK044510] KLA .96 1.07 1.03 1.05 1.00 1.06 1.16
ATP 1.04 1.04 1.04 1.04 1.05 1.08 1.01
KLA/ATP .96 1.08 1.07 1.10 1.12 1.08 1.01
Akt1
KLA  ATP  ATP+KLA
 NM_009652 thymoma viral proto-oncogene 1 (Akt1), mRNA [NM_009652] KLA .80 .80 .75 .75 .71 .70 .82
ATP 1.00 1.02 .76 .85 .76 .68 .84
KLA/ATP .82 .80 .64 .68 .67 .61 .72
Akt2
KLA  ATP  ATP+KLA
 NM_007434 thymoma viral proto-oncogene 2 (Akt2), transcript variant 2, mRNA [NM_007434] KLA 1.45 1.49 1.81 1.61 1.83 1.17 .92
ATP 1.12 1.12 1.00 1.28 1.20 .94 1.06
KLA/ATP 1.48 1.70 1.69 1.58 1.57 1.32 1.27
Akt3
KLA  ATP  ATP+KLA
 NM_011785 thymoma viral proto-oncogene 3 (Akt3), mRNA [NM_011785] KLA 3.42 3.45 5.31 5.16 4.65 3.80 2.12
ATP 1.12 1.22 1.10 1.37 1.02 1.11 1.56
KLA/ATP 3.72 4.17 4.62 4.64 2.74 2.05 3.82
Apaf1
KLA  ATP  ATP+KLA
 NM_001042558 apoptotic peptidase activating factor 1 (Apaf1), transcript variant 1, mRNA [NM_001042558] KLA 2.92 2.81 3.22 2.74 2.42 1.74 1.40
ATP 1.05 .99 .87 .81 1.61 2.03 1.46
KLA/ATP 2.90 2.78 2.01 1.69 1.56 2.77 2.73
BC010335
KLA  ATP  ATP+KLA
 BC010335 fibronectin 1, mRNA (cDNA clone IMAGE:3156499), **** WARNING: chimeric clone ****. [BC010335] KLA .94 .88 1.01 .99 .95 .95 1.07
ATP 1.06 .98 1.20 1.30 1.07 .97 .97
KLA/ATP .93 1.00 1.07 1.20 1.02 .96 .94
Bcl2
KLA  ATP  ATP+KLA
 NM_009741 B-cell leukemia/lymphoma 2 (Bcl2), transcript variant 1, mRNA [NM_009741] KLA .30 .26 .25 .25 .34 .38 .26
ATP .97 .89 1.50 1.04 .99 .29 .52
KLA/ATP .28 .26 .40 .33 .62 .29 .12
Bcl2
KLA  ATP  ATP+KLA
 NM_177410 B-cell leukemia/lymphoma 2 (Bcl2), transcript variant 2, mRNA [NM_177410] KLA .33 .33 .37 .42 .49 .46 .39
ATP 1.07 1.12 1.22 1.56 1.00 .38 .76
KLA/ATP .35 .34 .54 .89 .76 .36 .23
Bcl2l1
KLA  ATP  ATP+KLA
 NM_009743 Bcl2-like 1 (Bcl2l1), nuclear gene encoding mitochondrial protein, mRNA [NM_009743] KLA .99 1.02 1.10 1.16 1.27 .97 1.05
ATP 1.18 1.42 .81 1.26 1.51 .71 1.67
KLA/ATP 1.21 1.30 .66 1.15 1.31 1.17 1.59
Birc2
KLA  ATP  ATP+KLA
 NM_007465 baculoviral IAP repeat-containing 2 (Birc2), mRNA [NM_007465] KLA 4.63 4.59 3.77 2.79 2.32 2.07 1.84
ATP .95 .88 .84 .92 .76 1.34 1.28
KLA/ATP 4.70 4.93 4.13 2.60 1.34 1.60 2.31
Birc3
KLA  ATP  ATP+KLA
 BC011338 baculoviral IAP repeat-containing 3, mRNA (cDNA clone MGC:18386 IMAGE:3661563), complete cds [BC011338] KLA 5.48 5.46 4.94 4.16 4.91 3.36 3.74
ATP 1.05 1.08 4.21 4.28 2.59 2.55 1.57
KLA/ATP 6.78 8.91 11.01 4.87 2.28 2.12 3.66
Birc3
KLA  ATP  ATP+KLA
 NM_007464 baculoviral IAP repeat-containing 3 (Birc3), mRNA [NM_007464] KLA 17.83 15.88 13.48 11.14 11.79 6.90 6.10
ATP 1.14 1.16 1.70 4.07 5.00 6.33 2.41
KLA/ATP 14.77 16.44 19.09 13.91 8.27 6.22 7.73
Birc7
KLA  ATP  ATP+KLA
 AK053463 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130019N06 product:weakly similar to BA261N11.1.3 (BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7 (LIVIN), ISOFORM 3) (FRAGMENT) [Homo sapiens], full insert sequence [AK05 KLA 1.02 1.02 .93 1.01 .91 1.27 1.07
ATP 1.02 1.03 .99 .93 .96 .98 1.01
KLA/ATP 1.00 1.04 .97 .94 .91 .93 .92
Casp9
KLA  ATP  ATP+KLA
 NM_015733 caspase 9 (Casp9), mRNA [NM_015733] KLA .31 .31 .40 .66 .89 1.19 .91
ATP .88 .77 .91 .59 .43 .75 .93
KLA/ATP .26 .26 .30 .28 .80 1.06 .97
Ccnd1
KLA  ATP  ATP+KLA
 S78355 gb|Cyl-1=cyclin D1 [mice, BALB/c, brain, mRNA, 3737 nt]. [S78355] KLA .24 .23 .23 .24 .29 .47 .17
ATP 1.02 1.02 .88 .80 .52 .10 .21
KLA/ATP .27 .23 .22 .24 .27 .25 .14
Ccne1
KLA  ATP  ATP+KLA
 NM_007633 cyclin E1 (Ccne1), mRNA [NM_007633] KLA 1.13 1.14 1.13 .78 .51 .69 .55
ATP .92 .94 1.09 .93 .75 .71 .47
KLA/ATP 1.13 1.17 1.45 1.24 1.33 1.50 .85
Ccne2
KLA  ATP  ATP+KLA
 NM_001037134 cyclin E2 (Ccne2), transcript variant 1, mRNA [NM_001037134] KLA .34 .35 .42 .36 .35 .36 .26
ATP 1.02 1.11 1.01 .82 .58 .38 .23
KLA/ATP .36 .34 .44 .43 .41 .40 .25
Cdk2
KLA  ATP  ATP+KLA
 NM_016756 cyclin-dependent kinase 2 (Cdk2), transcript variant 2, mRNA [NM_016756] KLA .68 .67 .62 .63 .60 .74 .73
ATP 1.02 1.14 .91 .92 .68 .71 .65
KLA/ATP .67 .64 .64 .64 .61 .74 .62
Cdk4
KLA  ATP  ATP+KLA
 NM_009870 cyclin-dependent kinase 4 (Cdk4), mRNA [NM_009870] KLA .66 .72 .65 .55 .46 .50 .71
ATP 1.03 1.02 .53 .65 .66 .63 .75
KLA/ATP .78 .61 .31 .42 .44 .62 .43
Cdk6
KLA  ATP  ATP+KLA
 AK030810 adult male thymus cDNA, RIKEN full-length enriched library, clone:5830411I20 product:unclassifiable, full insert sequence [AK030810] KLA 1.05 .96 .67 .51 .48 .49 .45
ATP 1.02 .91 .78 .49 .50 .47 .44
KLA/ATP 1.01 .89 .65 .40 .36 .26 .49
Cdk6
KLA  ATP  ATP+KLA
 NM_009873 cyclin-dependent kinase 6 (Cdk6), mRNA [NM_009873] KLA 2.63 2.36 2.14 1.80 1.55 1.32 1.03
ATP 1.11 1.21 1.06 1.23 .94 1.30 2.08
KLA/ATP 2.58 2.69 2.24 2.25 1.38 .85 3.00
Cdkn1b
KLA  ATP  ATP+KLA
 NM_009875 cyclin-dependent kinase inhibitor 1B (Cdkn1b), mRNA [NM_009875] KLA .81 .84 .84 .91 .93 .88 .97
ATP .99 1.09 .97 1.06 1.48 .94 .91
KLA/ATP .83 .91 1.04 1.36 1.48 1.06 1.09
Cdkn2b
KLA  ATP  ATP+KLA
 NM_007670 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (Cdkn2b), mRNA [NM_007670] KLA .70 .75 .94 1.44 1.66 .55 .81
ATP 1.02 .89 1.00 .86 1.33 3.87 .57
KLA/ATP .71 .77 .91 .94 .74 1.64 1.17
Chuk
KLA  ATP  ATP+KLA
 NM_007700 conserved helix-loop-helix ubiquitous kinase (Chuk), mRNA [NM_007700] KLA 1.32 1.42 1.41 1.17 1.32 1.22 1.40
ATP 1.22 1.30 1.18 .97 1.02 1.00 1.37
KLA/ATP 1.56 1.61 1.21 1.09 .83 .84 1.17
Cks1b
KLA  ATP  ATP+KLA
 NM_016904 CDC28 protein kinase 1b (Cks1b), mRNA [NM_016904] KLA .63 .61 .51 .46 .26 .18 .18
ATP .92 .90 1.37 1.39 1.12 .57 .11
KLA/ATP .56 .59 .71 .75 .63 .26 .06
Cks2
KLA  ATP  ATP+KLA
 NM_025415 CDC28 protein kinase regulatory subunit 2 (Cks2), mRNA [NM_025415] KLA .52 .50 .48 .49 .35 .27 .19
ATP .92 .98 1.53 1.98 2.18 1.57 .12
KLA/ATP .48 .49 .81 1.20 2.25 1.82 .29
Col4a1
KLA  ATP  ATP+KLA
 NM_009931 collagen, type IV, alpha 1 (Col4a1), mRNA [NM_009931] KLA 1.13 1.19 1.12 1.09 1.04 .89 .90
ATP 1.01 1.17 1.02 1.04 .91 .89 .97
KLA/ATP 1.14 1.24 1.03 1.15 .95 .86 1.01
Col4a2
KLA  ATP  ATP+KLA
 NM_009932 collagen, type IV, alpha 2 (Col4a2), mRNA [NM_009932] KLA 1.30 1.45 1.54 1.40 1.71 1.71 2.12
ATP 1.09 1.07 .98 1.03 .92 1.21 1.42
KLA/ATP 1.45 1.53 1.24 1.29 1.16 1.57 3.31
Col4a3
KLA  ATP  ATP+KLA
 NM_007734 collagen, type IV, alpha 3 (Col4a3), mRNA [NM_007734] KLA 1.09 1.11 1.12 1.10 1.05 1.06 1.04
ATP 1.02 1.03 1.01 .99 1.01 1.07 1.07
KLA/ATP 1.04 1.13 1.01 1.09 1.02 .98 1.01
Col4a4
KLA  ATP  ATP+KLA
 NM_007735 collagen, type IV, alpha 4 (Col4a4), mRNA [NM_007735] KLA 1.35 1.29 1.33 1.39 1.30 1.18 .98
ATP 1.14 1.08 1.30 1.54 1.54 1.34 .93
KLA/ATP 1.37 1.41 1.70 1.88 1.67 1.29 1.19
Col4a5
KLA  ATP  ATP+KLA
 NM_007736 collagen, type IV, alpha 5 (Col4a5), mRNA [NM_007736] KLA 1.00 .95 .95 .82 .72 .58 .70
ATP 1.05 1.18 .98 .88 .56 .53 .57
KLA/ATP 1.04 1.05 .83 .82 .58 .49 .61
Col4a6
KLA  ATP  ATP+KLA
 NM_053185 collagen, type IV, alpha 6 (Col4a6), mRNA [NM_053185] KLA 1.06 1.04 1.00 1.07 .94 .93 .94
ATP .97 .96 1.18 1.10 1.07 1.04 .86
KLA/ATP 1.00 1.05 1.22 1.06 1.12 1.02 .93
Cycs
KLA  ATP  ATP+KLA
 NM_007808 cytochrome c, somatic (Cycs), nuclear gene encoding mitochondrial protein, mRNA [NM_007808] KLA 2.20 2.21 2.35 2.69 2.62 3.22 2.14
ATP .87 .89 1.31 1.05 1.06 1.20 1.26
KLA/ATP 1.88 2.04 2.86 2.26 2.57 2.45 2.03
Cyct
KLA  ATP  ATP+KLA
 NM_009989 cytochrome c, testis (Cyct), mRNA [NM_009989] KLA .93 1.01 1.00 .99 1.02 1.03 .96
ATP 1.01 .91 1.01 .99 .98 .95 .95
KLA/ATP 1.10 .96 .89 .89 1.10 1.05 .97
E2f1
KLA  ATP  ATP+KLA
 NM_007891 E2F transcription factor 1 (E2f1), mRNA [NM_007891] KLA .41 .44 .42 .41 .48 .77 .90
ATP 1.01 1.09 1.04 1.13 .83 .53 .84
KLA/ATP .44 .44 .52 .50 .49 .46 .85
E2f2
KLA  ATP  ATP+KLA
 NM_177733 E2F transcription factor 2 (E2f2), mRNA [NM_177733] KLA .13 .13 .14 .20 .19 .19 .18
ATP 1.08 .92 1.01 .85 .65 .38 .38
KLA/ATP .13 .13 .21 .20 .32 .24 .26
E2f3
KLA  ATP  ATP+KLA
 AK085296 0 day neonate kidney cDNA, RIKEN full-length enriched library, clone:D630007K21 product:E2F transcription factor 3, full insert sequence. [AK085296] KLA .98 .97 1.02 1.00 .99 .99 .99
ATP .97 1.06 1.03 .98 1.01 .99 1.00
KLA/ATP 1.12 1.14 1.03 .99 .96 .93 .96
E2f3
KLA  ATP  ATP+KLA
 NM_010093 E2F transcription factor 3 (E2f3), mRNA [NM_010093] KLA 1.11 1.09 1.13 1.21 1.47 1.62 1.65
ATP .97 .98 1.08 1.15 1.45 1.73 1.80
KLA/ATP 1.21 1.13 1.07 1.20 1.45 1.56 1.62
Fhit
KLA  ATP  ATP+KLA
 NM_010210 fragile histidine triad gene (Fhit), mRNA [NM_010210] KLA 1.16 1.14 1.22 1.10 .91 .82 .65
ATP .99 1.04 1.10 1.38 1.12 .81 .50
KLA/ATP 1.14 1.21 1.11 1.20 .96 .80 .54
Fn1
KLA  ATP  ATP+KLA
 NM_010233 fibronectin 1 (Fn1), mRNA [NM_010233] KLA 1.23 1.30 1.38 1.12 1.16 1.00 .78
ATP 1.02 1.19 1.25 1.56 1.33 1.05 .95
KLA/ATP 1.36 1.51 1.34 1.70 1.20 1.06 .93
Ikbkb
KLA  ATP  ATP+KLA
 NM_010546 inhibitor of kappaB kinase beta (Ikbkb), mRNA [NM_010546] KLA 1.88 2.10 2.14 1.83 1.73 1.31 1.19
ATP .81 .74 .55 .49 .59 1.05 .96
KLA/ATP 1.86 1.73 1.39 1.12 .89 1.17 1.24
Ikbkg
KLA  ATP  ATP+KLA
 AK042138 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630062P04 product:unclassifiable, full insert sequence. [AK042138] KLA .92 .87 .78 .78 .87 .88 .62
ATP .84 .71 .80 .50 1.15 2.33 .61
KLA/ATP .72 .69 .74 .48 1.06 1.97 .68
Ikbkg
KLA  ATP  ATP+KLA
 NM_010547 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 1, mRNA [NM_010547] KLA 1.51 1.63 1.74 1.83 1.83 1.73 1.72
ATP .80 .79 .82 .75 .66 2.58 2.37
KLA/ATP 1.43 1.42 1.17 1.04 .71 1.54 3.17
Ikbkg
KLA  ATP  ATP+KLA
 NM_178590 inhibitor of kappaB kinase gamma (Ikbkg), transcript variant 2, mRNA [NM_178590] KLA .84 .93 .86 .91 1.03 .89 .88
ATP 1.03 .98 .68 .56 .51 .93 .68
KLA/ATP .89 .81 .55 .52 .41 .67 .65
Itga2
KLA  ATP  ATP+KLA
 NM_008396 integrin alpha 2 (Itga2), mRNA [NM_008396] KLA 1.03 1.00 .98 1.01 .97 .96 1.00
ATP 1.05 .99 .93 1.02 1.04 1.03 .97
KLA/ATP .98 1.06 1.03 1.00 1.00 1.01 1.01
Itga2b
KLA  ATP  ATP+KLA
 NM_010575 integrin alpha 2b (Itga2b), mRNA [NM_010575] KLA 1.01 1.00 .98 1.04 1.01 1.04 1.18
ATP 1.01 .98 .95 1.02 .96 1.13 1.08
KLA/ATP 1.04 1.02 1.02 .95 1.05 1.53 1.23
Itga3
KLA  ATP  ATP+KLA
 NM_013565 integrin alpha 3 (Itga3), mRNA [NM_013565] KLA 1.06 1.09 1.10 1.17 1.19 1.29 1.41
ATP .99 .99 1.05 1.12 1.20 1.25 1.33
KLA/ATP 1.08 1.14 1.15 1.27 1.28 1.20 1.39
Itga6
KLA  ATP  ATP+KLA
 BC024571 integrin alpha 6, mRNA (cDNA clone IMAGE:5036677). [BC024571] KLA .44 .44 .37 .28 .25 .29 .34
ATP .96 1.01 .90 .58 .35 .11 .22
KLA/ATP .44 .41 .34 .23 .15 .09 .08
Itga6
KLA  ATP  ATP+KLA
 NM_008397 integrin alpha 6 (Itga6), mRNA [NM_008397] KLA .57 .58 .51 .45 .43 .44 .47
ATP 1.05 1.12 .86 .90 .57 .27 .36
KLA/ATP .64 .67 .50 .57 .39 .29 .26
Itgav
KLA  ATP  ATP+KLA
 AK052514 13 days embryo lung cDNA, RIKEN full-length enriched library, clone:D430040G12 product:hypothetical protein, full insert sequence. [AK052514] KLA 1.04 .93 1.05 1.02 1.01 .93 1.03
ATP 1.05 1.04 1.13 1.12 1.12 .91 1.02
KLA/ATP 1.08 .97 1.02 .95 1.01 .96 1.05
Itgav
KLA  ATP  ATP+KLA
 AK171739 activated spleen cDNA, RIKEN full-length enriched library, clone:F830008B15 product:unclassifiable, full insert sequence. [AK171739] KLA 1.04 .97 1.06 .95 1.15 .89 1.11
ATP 1.41 1.54 1.64 2.24 2.74 1.24 1.18
KLA/ATP 1.09 1.07 1.03 1.01 1.72 1.24 1.10
Itgav
KLA  ATP  ATP+KLA
 NM_008402 integrin alpha V (Itgav), mRNA [NM_008402] KLA 4.00 3.99 3.28 2.24 1.57 .95 1.13
ATP 1.14 1.22 1.13 1.39 2.22 2.47 1.70
KLA/ATP 4.59 4.61 2.48 2.44 1.60 1.88 2.56
Itgb1
KLA  ATP  ATP+KLA
 NM_010578 integrin beta 1 (fibronectin receptor beta) (Itgb1), mRNA [NM_010578] KLA 1.05 1.09 1.13 .92 1.01 .93 .88
ATP 1.14 1.30 .92 1.07 1.04 .83 .70
KLA/ATP 1.26 1.30 .87 1.02 .66 .65 .62
Itgb1
KLA  ATP  ATP+KLA
 U37029 integrin beta1D mRNA, partial cds. [U37029] KLA .93 .95 .96 1.01 .97 1.01 .98
ATP 1.05 .99 .99 1.03 1.03 .97 .94
KLA/ATP .99 .98 1.04 .97 1.02 1.01 .99
Lama1
KLA  ATP  ATP+KLA
 NM_008480 laminin, alpha 1 (Lama1), mRNA [NM_008480] KLA .99 1.04 .97 .96 1.01 .99 1.05
ATP 1.01 .99 .98 1.05 .99 1.09 .99
KLA/ATP 1.00 .97 .86 1.04 1.05 .99 1.00
Lama2
KLA  ATP  ATP+KLA
 AK046114 adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230342M05 product:laminin, alpha 2, full insert sequence. [AK046114] KLA 1.06 1.00 .95 1.10 1.04 .99 .96
ATP .98 1.09 1.00 .97 .96 1.12 1.01
KLA/ATP .94 1.04 1.05 1.00 .99 1.00 .98
Lama2
KLA  ATP  ATP+KLA
 NM_008481 laminin, alpha 2 (Lama2), mRNA [NM_008481] KLA .96 .99 .96 1.02 .95 1.00 .97
ATP 1.05 1.00 1.01 .94 1.01 1.04 .96
KLA/ATP .99 1.04 1.06 1.10 .98 .95 .97
Lama2
KLA  ATP  ATP+KLA
 U12147 laminin-2 alpha2 chain mRNA, complete cds. [U12147] KLA .96 1.00 .99 1.00 .98 1.02 1.03
ATP 1.01 .99 1.02 1.04 1.01 .99 1.02
KLA/ATP 1.00 1.01 1.00 1.01 .99 1.04 1.00
Lama3
KLA  ATP  ATP+KLA
 XM_140451 gb|PREDICTED: Mus musculus laminin, alpha 3, transcript variant 1 (Lama3), mRNA [XM_140451] KLA .76 .75 .73 .75 .71 .74 .67
ATP 1.04 1.12 1.05 1.20 .88 .73 .78
KLA/ATP .77 .81 .78 .82 .78 .71 .70
Lama4
KLA  ATP  ATP+KLA
 NM_010681 laminin, alpha 4 (Lama4), mRNA [NM_010681] KLA .99 .99 1.01 1.02 .98 .97 .96
ATP 1.00 1.08 1.05 1.05 1.03 1.04 .96
KLA/ATP 1.00 1.03 .93 1.00 .94 .90 .95
Lama5
KLA  ATP  ATP+KLA
 NM_001081171 laminin, alpha 5 (Lama5), mRNA [NM_001081171] KLA 1.11 1.07 1.09 1.00 .96 1.00 1.01
ATP 1.01 .99 1.03 1.01 1.00 .99 .99
KLA/ATP 1.12 1.08 1.05 1.04 .99 1.09 1.04
Lamb1-1
KLA  ATP  ATP+KLA
 NM_008482 laminin B1 subunit 1 (Lamb1-1), mRNA [NM_008482] KLA .93 .99 1.10 1.01 .95 1.00 .86
ATP .99 1.13 1.06 .99 1.07 .99 .97
KLA/ATP 1.00 1.06 .98 .95 .93 .89 1.04
Lamb2
KLA  ATP  ATP+KLA
 NM_008483 laminin, beta 2 (Lamb2), mRNA [NM_008483] KLA .93 .90 .95 .81 .79 .58 .37
ATP 1.01 1.09 .95 .99 .80 .81 .38
KLA/ATP .96 .87 1.00 .91 .72 .60 .38
Lamb3
KLA  ATP  ATP+KLA
 NM_008484 laminin, beta 3 (Lamb3), mRNA [NM_008484] KLA 1.00 .97 1.02 .98 1.00 1.04 .93
ATP 1.01 1.01 .91 .97 .89 1.04 1.03
KLA/ATP 1.00 .95 .97 1.00 .95 .87 1.02
Lamc1
KLA  ATP  ATP+KLA
 J03484 gb|Mouse laminin B2 chain mRNA, complete cds [J03484] KLA 1.14 1.01 1.04 .87 .82 .63 .75
ATP .99 1.09 1.07 1.14 1.36 2.38 .66
KLA/ATP 1.04 1.10 .95 1.12 1.30 1.70 .68
Lamc2
KLA  ATP  ATP+KLA
 AF106279 laminin gamma2 chain mRNA, partial cds. [AF106279] KLA 1.03 1.04 1.03 1.09 .97 .97 .98
ATP 1.04 1.04 1.16 1.48 1.46 1.29 1.26
KLA/ATP 1.04 1.00 1.03 1.06 .95 .99 1.08
Lamc2
KLA  ATP  ATP+KLA
 NM_008485 laminin, gamma 2 (Lamc2), mRNA [NM_008485] KLA 1.16 1.22 1.23 1.07 1.04 1.12 1.04
ATP 1.01 1.10 2.81 4.58 4.35 3.34 2.36
KLA/ATP 1.31 1.29 1.41 1.40 1.28 1.25 1.49
Lamc3
KLA  ATP  ATP+KLA
 AF083372 laminin 12 gamma 3 chain mRNA, complete cds. [AF083372] KLA .96 .94 .99 .96 .94 1.02 .88
ATP 1.06 1.00 .95 .98 .98 .99 1.02
KLA/ATP .90 .98 1.03 .95 .88 .97 .96
Lamc3
KLA  ATP  ATP+KLA
 NM_011836 laminin gamma 3 (Lamc3), mRNA [NM_011836] KLA 1.00 1.00 1.04 1.04 1.03 1.01 .97
ATP .99 1.06 1.00 .91 .98 .96 1.01
KLA/ATP .98 1.04 1.01 1.02 .96 .95 .98
Max
KLA  ATP  ATP+KLA
 NM_008558 Max protein (Max), mRNA [NM_008558] KLA 3.40 3.25 4.09 4.53 3.19 2.71 1.19
ATP 1.17 1.09 1.13 .86 1.24 1.40 1.09
KLA/ATP 3.14 3.36 5.49 3.83 4.35 2.96 1.67
Mm.18787
9
KLA  ATP  ATP+KLA
 149250519 Unknown KLA .98 .98 1.02 1.05 1.01 1.10 1.02
ATP 1.03 1.00 .98 1.02 1.02 1.04 .99
KLA/ATP .99 1.07 1.04 1.02 .94 .97 .93
Mm.19309
9
KLA  ATP  ATP+KLA
 46849811 Unknown KLA 1.32 1.36 1.42 1.17 1.06 .90 .58
ATP .98 1.12 1.41 1.81 1.44 1.14 .89
KLA/ATP 1.39 1.55 1.57 2.02 1.43 1.12 .74
Mm.21312
8
KLA  ATP  ATP+KLA
 141801344 Unknown KLA .96 .95 .83 .77 .52 .99 1.32
ATP .80 .82 1.09 .80 .83 1.19 1.46
KLA/ATP .78 .92 .98 .62 .71 .94 1.41
Mm.25381
9
KLA  ATP  ATP+KLA
 118130676 Unknown KLA 1.81 1.88 1.96 1.62 1.89 2.44 1.56
ATP .92 .91 1.24 1.01 1.16 2.06 1.95
KLA/ATP 1.62 1.86 1.86 1.41 1.89 2.37 1.97
Mm.25806
5
KLA  ATP  ATP+KLA
 148747407 Unknown KLA 1.05 1.02 1.03 1.00 .99 1.05 .94
ATP .98 .98 1.03 1.02 .99 1.06 1.03
KLA/ATP 1.01 1.02 1.03 1.01 .96 .98 1.01
Mm.27304
9
KLA  ATP  ATP+KLA
 119672895 Unknown KLA .23 .22 .22 .22 .30 .51 .16
ATP 1.08 1.05 .88 .78 .47 .09 .20
KLA/ATP .28 .22 .21 .24 .26 .22 .12
Mm.30793
2
KLA  ATP  ATP+KLA
 160333363 Unknown KLA .13 .12 .14 .16 .15 .18 .15
ATP .92 .94 1.12 .93 .58 .29 .31
KLA/ATP .11 .11 .18 .20 .28 .20 .19
Mm.33565
9
KLA  ATP  ATP+KLA
 160333365 Unknown KLA 5.54 4.69 3.93 3.03 2.00 1.91 1.69
ATP .98 .81 1.01 .78 .68 1.71 1.10
KLA/ATP 5.05 4.44 5.07 2.38 1.34 1.88 2.00
Mm.35584
KLA  ATP  ATP+KLA
 70909358 Unknown KLA .22 .25 .28 .33 .40 .77 .46
ATP 1.05 .96 1.08 .56 1.10 .79 .74
KLA/ATP .23 .25 .32 .25 .90 1.02 .60
Mm.46002
4
KLA  ATP  ATP+KLA
 38348245 Unknown KLA 1.22 1.25 1.25 1.19 1.22 1.47 1.14
ATP 1.03 .94 1.01 1.01 2.67 2.31 1.37
KLA/ATP 1.35 1.19 1.27 1.22 1.99 1.83 1.45
Mm.46042
5
KLA  ATP  ATP+KLA
 145699103 Unknown KLA .97 1.06 1.00 1.00 1.04 1.00 1.06
ATP .98 1.03 .96 .96 1.00 1.05 .96
KLA/ATP .99 .95 1.04 .97 1.01 .98 .93
Myc
KLA  ATP  ATP+KLA
 NM_010849 myelocytomatosis oncogene (Myc), mRNA [NM_010849] KLA .38 .31 .45 .45 .49 .35 .33
ATP 1.05 1.09 1.72 4.41 1.28 .45 .76
KLA/ATP .37 .30 .44 1.23 .34 .17 .19
Nfkb1
KLA  ATP  ATP+KLA
 BC050841 nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, mRNA (cDNA clone IMAGE:6392793), complete cds. [BC050841] KLA 5.81 4.96 4.77 3.21 3.37 2.00 1.71
ATP 1.39 1.52 3.25 12.63 13.64 4.80 1.08
KLA/ATP 7.21 8.69 19.53 23.93 11.70 2.85 2.01
Nfkb1
KLA  ATP  ATP+KLA
 M57999 gb|Mouse transcription factor NF-kappa-B DNA binding subunit mRNA, complete cds. [M57999] KLA 8.55 7.87 7.35 6.13 3.51 1.85 1.38
ATP .98 .96 1.21 3.06 5.29 4.67 .69
KLA/ATP 7.32 7.20 8.71 10.82 5.55 2.77 1.54
Nfkbia
KLA  ATP  ATP+KLA
 NM_010907 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia), mRNA [NM_010907] KLA 18.65 18.46 13.63 17.88 14.25 9.17 7.92
ATP .91 1.09 7.11 32.39 17.44 10.49 1.72
KLA/ATP 15.57 17.66 15.73 23.91 13.83 10.73 9.48
Nos2
KLA  ATP  ATP+KLA
 NM_010927 nitric oxide synthase 2, inducible, macrophage (Nos2), mRNA [NM_010927] KLA 13.50 16.36 25.65 23.25 24.78 15.99 6.48
ATP 1.03 1.03 1.48 1.66 1.65 5.55 1.70
KLA/ATP 16.01 17.41 19.06 25.50 20.84 29.92 29.80
Pias2
KLA  ATP  ATP+KLA
 NM_008602 protein inhibitor of activated STAT 2 (Pias2), mRNA [NM_008602] KLA .85 .84 .82 .87 .80 1.05 1.03
ATP .88 .95 1.02 .86 .93 1.17 1.16
KLA/ATP .76 .83 .91 .77 .93 1.15 1.16
Pik3ca
KLA  ATP  ATP+KLA
 ENSMUST00000108243 ens|Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K). [Source:Uniprot/SWISSPROT;Acc:P42337] [ENSMUST00000108243] KLA 1.07 1.01 .91 .90 .98 .96 .86
ATP 1.03 .87 1.12 .63 1.22 1.86 .60
KLA/ATP 1.05 .82 .91 .61 1.17 1.26 .63
Pik3ca
KLA  ATP  ATP+KLA
 NM_008839 phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (Pik3ca), mRNA [NM_008839] KLA 1.15 1.11 1.05 .82 .99 1.03 1.27
ATP .98 1.00 .79 .75 .96 1.32 1.10
KLA/ATP 1.10 .98 .64 .72 .80 1.20 1.41
Pik3cb
KLA  ATP  ATP+KLA
 NM_029094 phosphatidylinositol 3-kinase, catalytic, beta polypeptide (Pik3cb), mRNA [NM_029094] KLA 1.06 1.06 1.03 .73 .68 .98 1.69
ATP 1.04 1.21 .95 1.02 .85 .93 1.73
KLA/ATP 1.15 1.27 .73 .83 .58 .81 1.81
Pik3cd
KLA  ATP  ATP+KLA
 NM_008840 phosphatidylinositol 3-kinase catalytic delta polypeptide (Pik3cd), transcript variant 1, mRNA [NM_008840] KLA 2.28 2.42 3.10 4.17 3.35 2.31 1.34
ATP 1.02 .91 .99 .63 .30 .67 .80
KLA/ATP 2.14 2.23 2.70 1.51 1.17 .85 .72
Pik3cd
KLA  ATP  ATP+KLA
 U86587 phosphatidylinositol 3-kinase catalytic subunit p110 delta mRNA, complete cds. [U86587] KLA 2.21 2.24 3.71 3.17 3.67 2.66 1.48
ATP 1.00 1.03 .93 .96 .46 .75 .97
KLA/ATP 2.27 2.32 1.97 2.02 1.01 .99 .98
Pik3cg
KLA  ATP  ATP+KLA
 NM_020272 phosphoinositide-3-kinase, catalytic, gamma polypeptide (Pik3cg), mRNA [NM_020272] KLA .53 .53 .61 .64 .97 .86 .79
ATP 1.01 1.13 .88 .89 .52 .53 .53
KLA/ATP .58 .53 .43 .60 .40 .43 .62
Pik3r1
KLA  ATP  ATP+KLA
 NM_001077495 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) (Pik3r1), transcript variant 2, mRNA [NM_001077495] KLA 1.05 1.07 1.03 1.00 1.01 1.20 .85
ATP .97 1.02 1.48 1.42 1.76 1.33 1.23
KLA/ATP 1.11 1.12 1.06 1.17 1.24 .99 1.12
Pik3r2
KLA  ATP  ATP+KLA
 NM_008841 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2), mRNA [NM_008841] KLA .50 .50 .48 .43 .46 .66 .75
ATP .78 .68 .45 .43 .28 .57 1.37
KLA/ATP .49 .38 .32 .33 .38 .67 1.10
Pik3r3
KLA  ATP  ATP+KLA
 NM_181585 phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) (Pik3r3), mRNA [NM_181585] KLA 1.59 1.49 1.37 1.17 1.05 1.55 1.41
ATP 1.12 1.00 1.33 1.70 2.01 2.37 2.02
KLA/ATP 1.63 1.54 1.58 1.70 2.43 2.68 1.92
Pik3r5
KLA  ATP  ATP+KLA
 NM_177320 phosphoinositide-3-kinase, regulatory subunit 5, p101 (Pik3r5), mRNA [NM_177320] KLA 3.57 3.58 4.16 3.54 4.11 2.59 2.39
ATP 1.08 1.08 .93 1.67 3.11 1.88 1.34
KLA/ATP 3.91 3.70 3.30 3.80 2.70 2.04 3.00
Pten
KLA  ATP  ATP+KLA
 NM_008960 phosphatase and tensin homolog (Pten), mRNA [NM_008960] KLA .79 .73 .61 .59 .56 .70 1.00
ATP 1.04 1.11 1.07 1.12 1.03 1.38 .83
KLA/ATP .75 .69 .60 .74 .93 1.09 1.24
Ptgs2
KLA  ATP  ATP+KLA
 NM_011198 prostaglandin-endoperoxide synthase 2 (Ptgs2), mRNA [NM_011198] KLA 181.04 220.88 218.58 132.79 103.05 22.69 18.02
ATP 2.47 9.45 52.13 208.62 271.22 306.11 6.86
KLA/ATP 233.39 387.29 617.86 ###.## 608.44 290.80 112.22
Ptk2
KLA  ATP  ATP+KLA
 NM_007982 PTK2 protein tyrosine kinase 2 (Ptk2), mRNA [NM_007982] KLA .99 .99 1.02 1.04 1.09 1.22 1.57
ATP 1.04 1.09 .95 .98 .67 .96 .87
KLA/ATP .99 1.03 .87 .93 .81 1.16 1.04
Rarb
KLA  ATP  ATP+KLA
 NM_011243 retinoic acid receptor, beta (Rarb), mRNA [NM_011243] KLA 1.03 1.01 1.01 1.02 1.02 .98 1.00
ATP .99 1.00 1.02 1.01 .98 .98 .99
KLA/ATP 1.02 1.02 1.00 .99 .98 .98 .99
Rarb
KLA  ATP  ATP+KLA
 S92180 gb|Mus sp. retinoic acid receptor isoform RAR-beta 4 mRNA, partial cds. [S92180] KLA 1.04 .97 .96 1.04 1.01 1.05 1.00
ATP 1.03 .95 1.10 .96 1.03 1.05 .98
KLA/ATP 1.01 .97 1.06 .97 .98 .93 1.05
Rb1
KLA  ATP  ATP+KLA
 NM_009029 retinoblastoma 1 (Rb1), mRNA [NM_009029] KLA .67 .60 .55 .51 .46 .75 .79
ATP 1.04 1.01 1.12 .86 .59 .43 .76
KLA/ATP .64 .59 .58 .46 .36 .30 .65
Rela
KLA  ATP  ATP+KLA
 NM_009045 v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Rela), mRNA [NM_009045] KLA 2.05 2.05 2.07 1.75 1.83 1.58 1.33
ATP 1.03 1.08 1.10 1.44 1.61 2.48 1.05
KLA/ATP 2.17 2.27 2.05 2.47 1.93 2.35 2.02
Rxra
KLA  ATP  ATP+KLA
 NM_011305 retinoid X receptor alpha (Rxra), mRNA [NM_011305] KLA .53 .55 .50 .52 .54 .85 1.09
ATP .95 1.00 1.18 1.00 .82 1.20 1.65
KLA/ATP .57 .55 .58 .55 .67 1.07 1.57
Rxrb
KLA  ATP  ATP+KLA
 NM_011306 retinoid X receptor beta (Rxrb), mRNA [NM_011306] KLA .71 .75 .75 .76 .83 .81 .89
ATP 1.04 1.13 .94 1.20 1.13 .81 .75
KLA/ATP .80 .86 .72 .85 .83 .93 .92
Rxrg
KLA  ATP  ATP+KLA
 NM_009107 retinoid X receptor gamma (Rxrg), mRNA [NM_009107] KLA .98 1.07 1.07 1.00 1.00 1.00 1.07
ATP 1.02 1.03 1.06 1.06 1.11 1.01 .99
KLA/ATP .95 .97 1.05 1.05 1.09 .98 1.06
Skp2
KLA  ATP  ATP+KLA
 AF083215 SCF complex protein Skp2 mRNA, complete cds. [AF083215] KLA .36 .37 .34 .37 .44 .78 .60
ATP 1.05 1.35 .85 .66 .83 .54 .76
KLA/ATP .33 .39 .37 .37 .65 .73 .62
Traf1
KLA  ATP  ATP+KLA
 NM_009421 Tnf receptor-associated factor 1 (Traf1), mRNA [NM_009421] KLA 44.86 39.03 38.11 34.21 36.49 19.69 14.75
ATP 1.14 1.04 1.98 8.16 16.79 30.81 6.36
KLA/ATP 46.20 45.67 45.63 38.00 27.26 31.47 63.83
Traf2
KLA  ATP  ATP+KLA
 NM_009422 Tnf receptor-associated factor 2 (Traf2), mRNA [NM_009422] KLA 3.38 3.62 3.49 3.36 3.49 3.39 2.68
ATP .97 1.04 1.00 1.10 1.54 2.40 1.55
KLA/ATP 3.38 3.16 2.93 2.74 2.67 3.11 4.70
Traf3
KLA  ATP  ATP+KLA
 NM_011632 Tnf receptor-associated factor 3 (Traf3), transcript variant 1, mRNA [NM_011632] KLA .52 .49 .51 .49 .80 .98 1.22
ATP .93 .92 .95 1.13 2.70 1.80 1.42
KLA/ATP .56 .50 .49 1.07 2.94 1.92 1.65
Traf4
KLA  ATP  ATP+KLA
 NM_009423 Tnf receptor associated factor 4 (Traf4), mRNA [NM_009423] KLA .88 .85 .85 .84 .86 .88 .91
ATP .98 1.01 1.01 .96 1.05 1.29 .93
KLA/ATP .83 .86 .83 .94 1.01 1.11 .88
Traf5
KLA  ATP  ATP+KLA
 NM_011633 Tnf receptor-associated factor 5 (Traf5), mRNA [NM_011633] KLA 1.82 1.92 1.93 2.10 2.75 2.08 1.00
ATP 1.02 1.04 1.10 .78 3.79 2.22 1.42
KLA/ATP 1.70 1.89 1.85 1.64 5.40 2.10 1.83
Traf6
KLA  ATP  ATP+KLA
 NM_009424 Tnf receptor-associated factor 6 (Traf6), mRNA [NM_009424] KLA 1.19 1.28 1.34 1.20 1.23 1.23 1.28
ATP 1.06 1.12 .92 1.15 2.46 1.84 1.40
KLA/ATP 1.32 1.37 .89 1.16 1.45 1.49 1.46
Trp53
KLA  ATP  ATP+KLA
 NM_011640 transformation related protein 53 (Trp53), mRNA [NM_011640] KLA 1.25 1.37 1.11 .86 .72 .71 .95
ATP 1.15 1.32 .90 1.85 1.26 .68 .70
KLA/ATP 1.66 1.49 .80 1.76 .81 .65 .74
Xiap
KLA  ATP  ATP+KLA
 NM_009688 X-linked inhibitor of apoptosis (Xiap), mRNA [NM_009688] KLA 1.61 1.63 1.62 1.52 1.34 1.27 1.11
ATP 1.03 1.01 .99 .96 .88 1.19 1.25
KLA/ATP 1.64 1.63 1.54 1.33 1.08 1.19 1.72