Microarray analysis of bone marrow-derived macrophage cells treated with Kdo₂-lipid A (KLA) and ATP

Kdo₂-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Riboflavin metabolism (mmu00740)

Legend: : View data/graphs for replicates

Gene symbol	Time course plot	Accession	Description	Treatment	15min	30min	1hr	2hr	4hr	8hr	20hr
AK134499	KLA  ATP  ATP+KLA	AK134499	11 days embryo head cDNA, RIKEN full-length enriched library, clone:6230419C23 product:unclassifiable, full insert sequence [AK134499]	KLA	.97	1.04	.99	1.01	.93	1.08	1.21
				ATP	.97	1.02	.97	1.13	1.01	.98	1.06
				KLA/ATP	.95	.98	1.00	.95	1.00	.98	1.02
Acp1	KLA  ATP  ATP+KLA	NM_001110239	acid phosphatase 1, soluble (Acp1), transcript variant 1, mRNA [NM_001110239]	KLA	1.15	1.18	1.12	1.18	1.14	1.10	1.18
				ATP	.94	1.01	1.12	1.23	.90	.68	.98
				KLA/ATP	1.10	1.24	1.20	1.33	.94	.82	.99
Acp2	KLA  ATP  ATP+KLA	AK170658	NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630113A07 product:acid phosphatase 2, lysosomal, full insert sequence [AK170658]	KLA	1.17	1.24	1.33	1.51	2.46	3.34	3.43
				ATP	.95	.99	.76	1.07	.73	.56	.97
				KLA/ATP	1.23	1.23	.78	1.06	.72	.78	2.19
Acp2	KLA  ATP  ATP+KLA	NM_007387	acid phosphatase 2, lysosomal (Acp2), mRNA [NM_007387]	KLA	1.52	1.61	1.73	1.82	2.82	4.19	5.68
				ATP	1.12	1.21	.95	1.29	.87	.76	2.68
				KLA/ATP	1.81	1.80	1.24	1.72	1.04	1.16	5.43
Acp5	KLA  ATP  ATP+KLA	NM_007388	acid phosphatase 5, tartrate resistant (Acp5), transcript variant 3, mRNA [NM_007388]	KLA	3.62	3.55	3.27	3.26	3.31	3.93	5.79
				ATP	.96	1.00	1.29	1.96	2.30	3.05	3.81
				KLA/ATP	3.61	3.85	4.05	5.38	4.56	5.15	6.77
Acp6	KLA  ATP  ATP+KLA	NM_019800	acid phosphatase 6, lysophosphatidic (Acp6), mRNA [NM_019800]	KLA	.56	.47	.41	.37	.24	.32	.79
				ATP	.88	.80	1.06	.84	.62	.51	.67
				KLA/ATP	.49	.44	.49	.36	.34	.37	.39
Acpp	KLA  ATP  ATP+KLA	NM_019807	acid phosphatase, prostate (Acpp), transcript variant 2, mRNA [NM_019807]	KLA	1.09	1.07	1.11	1.23	1.20	1.08	1.14
				ATP	1.00	1.02	1.07	1.03	1.00	2.39	3.55
				KLA/ATP	1.02	1.12	1.04	1.10	1.05	1.69	4.36
Acpp	KLA  ATP  ATP+KLA	NM_207668	acid phosphatase, prostate (Acpp), transcript variant 1, mRNA [NM_207668]	KLA	1.15	1.01	1.13	1.13	1.12	1.06	1.12
				ATP	.96	1.02	1.04	1.02	.96	2.62	2.40
				KLA/ATP	1.00	1.04	1.09	1.08	1.15	1.91	2.69
Blvrb	KLA  ATP  ATP+KLA	NM_144923	biliverdin reductase B (flavin reductase (NADPH)) (Blvrb), mRNA [NM_144923]	KLA	.92	.92	.90	.97	1.03	1.08	1.45
				ATP	1.08	1.10	1.14	1.22	1.28	2.18	1.75
				KLA/ATP	.97	.92	.94	1.10	1.24	1.96	2.58
Enpp1	KLA  ATP  ATP+KLA	ENSMUST00000105520	ens|Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E- NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) (Lymphocyte antigen 41) (Ly-41) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1	KLA	.71	.79	.64	.61	.55	.51	.32
				ATP	.85	.97	.85	.72	.62	.45	.28
				KLA/ATP	.72	.73	.61	.66	.60	.55	.27
Enpp1	KLA  ATP  ATP+KLA	NM_008813	ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1), mRNA [NM_008813]	KLA	.82	.83	.77	.83	.65	.64	.51
				ATP	.89	.90	1.21	1.00	.98	.87	.64
				KLA/ATP	.72	.76	.96	.87	1.00	.94	.51
Enpp3	KLA  ATP  ATP+KLA	BC005527	ectonucleotide pyrophosphatase [BC005527]	KLA	1.06	.99	.98	1.01	.97	.99	.96
				ATP	.93	1.08	.99	1.05	.94	1.05	1.10
				KLA/ATP	.95	.96	1.10	.99	.95	.94	1.03
Enpp3	KLA  ATP  ATP+KLA	BC006944	ectonucleotide pyrophosphatase/phosphodiesterase 3, mRNA (cDNA clone IMAGE:2655671), complete cds. [BC006944]	KLA	1.02	1.01	1.03	1.08	1.04	1.01	1.01
				ATP	.97	1.01	.96	1.00	.98	1.07	.99
				KLA/ATP	1.01	.99	1.07	1.02	.97	.98	.92
Enpp3	KLA  ATP  ATP+KLA	NM_134005	ectonucleotide pyrophosphatase/phosphodiesterase 3 (Enpp3), mRNA [NM_134005]	KLA	1.01	.95	.99	.98	1.05	1.04	.98
				ATP	.98	.98	1.03	.98	.96	1.00	.98
				KLA/ATP	.97	1.03	1.04	.93	1.02	.99	1.04
Flad1	KLA  ATP  ATP+KLA	NM_177041	RFad1, flavin adenine dinucleotide synthetase, homolog (yeast) (Flad1), mRNA [NM_177041]	KLA	.86	.91	.90	1.00	1.13	1.42	1.85
				ATP	.94	.96	.95	.99	.68	1.02	2.24
				KLA/ATP	.84	.82	.78	.87	.70	1.08	2.77
Mm.23812 7	KLA  ATP  ATP+KLA	168823498	Unknown	KLA	1.07	.97	1.04	1.05	1.02	.98	1.02
				ATP	.95	1.00	.98	1.01	.95	.93	.92
				KLA/ATP	.93	.98	.98	1.04	1.01	1.02	.98
Mm.35983 1	KLA  ATP  ATP+KLA	159032061	Unknown	KLA	1.02	.93	.95	.94	1.01	.97	1.11
				ATP	.97	1.01	1.07	1.03	.93	1.03	1.02
				KLA/ATP	.94	.91	.99	.97	.97	.98	.91
Rfk	KLA  ATP  ATP+KLA	NM_019437	riboflavin kinase (Rfk), mRNA [NM_019437]	KLA	1.03	1.05	.97	.96	.86	.77	.86
				ATP	1.05	1.20	1.16	1.43	1.21	1.23	1.24
				KLA/ATP	1.04	1.09	.95	1.20	.91	.93	1.03
Tyr	KLA  ATP  ATP+KLA	NM_011661	tyrosinase (Tyr), mRNA [NM_011661]	KLA	.99	1.02	.99	1.01	1.00	1.01	1.03
				ATP	1.01	.98	.99	1.03	1.00	1.01	1.00
				KLA/ATP	1.01	1.00	1.00	1.01	1.00	1.03	.98