Microarray analysis of bone marrow-derived macrophage cells treated with Kdo₂-lipid A (KLA) and ATP

Kdo₂-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Other glycan degradation (mmu00511)

Legend: : View data/graphs for replicates

Gene symbol	Time course plot	Accession	Description	Treatment	15min	30min	1hr	2hr	4hr	8hr	20hr
AK209324	KLA  ATP  ATP+KLA	AK209324	cDNA, clone:Y2G0114L23, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000060207, based on BLAT search. [AK209324]	KLA	.48	.51	.55	.57	.80	.90	1.17
				ATP	1.01	.96	.73	.60	.76	.78	1.24
				KLA/ATP	.54	.46	.42	.54	.76	.76	.73
Aga	KLA  ATP  ATP+KLA	NM_001005847	aspartylglucosaminidase (Aga), mRNA [NM_001005847]	KLA	1.07	1.08	1.08	1.01	1.02	.98	1.30
				ATP	1.12	1.12	1.21	1.26	1.14	.91	1.51
				KLA/ATP	1.02	1.11	1.21	1.29	.94	.85	.94
D230014K 01Rik	KLA  ATP  ATP+KLA	NM_172573	RIKEN cDNA D230014K01 gene (D230014K01Rik), mRNA [NM_172573]	KLA	.54	.55	.44	.52	.50	.57	.72
				ATP	1.02	1.11	.99	.93	.47	.42	.69
				KLA/ATP	.53	.53	.56	.61	.54	.45	.54
Fuca1	KLA  ATP  ATP+KLA	NM_024243	fucosidase, alpha-L- 1, tissue (Fuca1), mRNA [NM_024243]	KLA	.72	.75	.70	.66	.61	.56	.59
				ATP	.97	1.06	.90	1.25	.93	.67	.99
				KLA/ATP	.77	.78	.65	.94	.66	.61	.92
Fuca2	KLA  ATP  ATP+KLA	NM_025799	fucosidase, alpha-L- 2, plasma (Fuca2), mRNA [NM_025799]	KLA	.83	.85	.80	.77	.68	.69	.90
				ATP	.98	1.00	1.15	1.07	1.13	.99	1.11
				KLA/ATP	.82	.83	.93	.85	.76	.72	.81
Gba	KLA  ATP  ATP+KLA	NM_001077411	glucosidase, beta, acid (Gba), mRNA [NM_001077411]	KLA	.86	.89	.92	.84	.95	1.11	1.65
				ATP	.97	.99	.60	.74	.63	.76	2.19
				KLA/ATP	.95	.85	.52	.74	.50	.81	2.57
Gba2	KLA  ATP  ATP+KLA	NM_172692	glucosidase beta 2 (Gba2), mRNA [NM_172692]	KLA	.43	.43	.47	.62	.82	.99	.91
				ATP	1.00	1.00	.97	.81	.53	.73	1.03
				KLA/ATP	.41	.43	.47	.47	.69	.88	1.21
Glb1	KLA  ATP  ATP+KLA	NM_009752	galactosidase, beta 1 (Glb1), mRNA [NM_009752]	KLA	.93	.96	1.02	.85	.86	.81	.80
				ATP	1.03	1.10	1.01	1.13	.97	.82	.75
				KLA/ATP	1.08	1.04	.86	1.06	.81	.81	.66
Hexa	KLA  ATP  ATP+KLA	NM_010421	hexosaminidase A (Hexa), mRNA [NM_010421]	KLA	.74	.76	.70	.63	.57	.52	.51
				ATP	.98	1.04	.82	.81	.68	.52	.64
				KLA/ATP	.76	.78	.63	.60	.48	.37	.31
Hexb	KLA  ATP  ATP+KLA	NM_010422	hexosaminidase B (Hexb), mRNA [NM_010422]	KLA	.82	.90	.81	.70	.64	.64	.71
				ATP	.95	1.03	1.11	.83	.72	.58	.63
				KLA/ATP	.80	.83	.77	.68	.53	.45	.50
Hexdc	KLA  ATP  ATP+KLA	NM_001001333	hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing (Hexdc), mRNA [NM_001001333]	KLA	.57	.61	.55	.60	.56	.65	1.03
				ATP	1.02	1.05	.87	.82	.60	.52	.73
				KLA/ATP	.63	.61	.58	.52	.48	.52	.77
Man2b1	KLA  ATP  ATP+KLA	AK054315	2 days pregnant adult female ovary cDNA, RIKEN full-length enriched library, clone:E330014I09 product:mannosidase 2, alpha B1, full insert sequence. [AK054315]	KLA	1.00	.97	.91	.97	.93	.92	.94
				ATP	.98	.99	.89	1.01	.92	.94	.97
				KLA/ATP	.94	.95	.90	.93	1.00	.94	.96
Man2b1	KLA  ATP  ATP+KLA	NM_010764	mannosidase 2, alpha B1 (Man2b1), mRNA [NM_010764]	KLA	.78	.76	.76	.67	.59	.51	.37
				ATP	.90	.94	.92	.84	.74	.54	.43
				KLA/ATP	.74	.77	.73	.64	.52	.37	.27
Man2b2	KLA  ATP  ATP+KLA	NM_008550	mannosidase 2, alpha B2 (Man2b2), mRNA [NM_008550]	KLA	1.13	1.07	.95	.98	.97	.76	.89
				ATP	1.17	1.29	1.18	1.52	1.04	.76	.66
				KLA/ATP	1.07	1.28	1.22	1.62	.79	.70	.68
Man2c1	KLA  ATP  ATP+KLA	NM_028636	mannosidase, alpha, class 2C, member 1 (Man2c1), mRNA [NM_028636]	KLA	.99	1.00	1.09	.95	.90	.79	.86
				ATP	1.05	1.12	1.09	1.19	.92	.71	.66
				KLA/ATP	1.04	1.06	1.02	1.10	.79	.72	.62
Manba	KLA  ATP  ATP+KLA	AK037629	16 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A130030I04 product:unclassifiable, full insert sequence. [AK037629]	KLA	1.01	.99	.98	1.09	1.04	1.02	1.01
				ATP	.97	1.00	.91	.99	.96	1.02	.99
				KLA/ATP	.97	1.03	.92	.96	1.04	.97	.93
Manba	KLA  ATP  ATP+KLA	NM_027288	mannosidase, beta A, lysosomal (Manba), mRNA [NM_027288]	KLA	.60	.62	.56	.49	.42	.55	.77
				ATP	.98	1.03	1.03	1.12	.93	.47	.75
				KLA/ATP	.63	.65	.58	.62	.51	.39	.76
Mm.10370 3	KLA  ATP  ATP+KLA	118131105	Unknown	KLA	1.00	1.01	.96	.80	.81	1.04	1.02
				ATP	.99	1.06	.98	.67	.72	.82	1.06
				KLA/ATP	1.02	1.12	.94	.76	.84	1.08	.93
Mm.27513 0	KLA  ATP  ATP+KLA	47679083	Unknown	KLA	.55	.51	.47	.48	.52	.68	.89
				ATP	.98	.82	.91	.61	.47	.57	.66
				KLA/ATP	.52	.46	.51	.35	.38	.47	.74
Neu1	KLA  ATP  ATP+KLA	NM_010893	neuraminidase 1 (Neu1), mRNA [NM_010893]	KLA	.59	.58	.57	.66	.88	1.30	1.59
				ATP	.98	1.01	1.08	1.31	1.76	2.01	2.47
				KLA/ATP	.57	.59	.70	.78	1.18	1.73	2.99
Neu2	KLA  ATP  ATP+KLA	NM_015750	neuraminidase 2 (Neu2), mRNA [NM_015750]	KLA	1.07	1.16	1.12	1.24	1.18	1.16	1.17
				ATP	1.13	1.11	1.15	1.12	1.08	1.07	1.05
				KLA/ATP	1.14	1.22	1.22	1.19	1.11	1.12	1.09
Neu3	KLA  ATP  ATP+KLA	NM_016720	neuraminidase 3 (Neu3), mRNA [NM_016720]	KLA	1.09	1.07	1.02	.92	.82	1.10	1.08
				ATP	.99	.87	1.06	.72	.82	.92	1.05
				KLA/ATP	1.08	1.04	1.02	.86	.94	1.24	1.02
Neu4	KLA  ATP  ATP+KLA	NM_173772	sialidase 4 (Neu4), mRNA [NM_173772]	KLA	1.00	.97	1.03	1.05	1.03	1.04	.99
				ATP	1.03	.99	.98	1.02	1.02	1.02	.90
				KLA/ATP	.92	1.06	1.03	.98	1.04	.95	1.06